Onconova Implementation Guide
0.2.0 - ci-build

Onconova Implementation Guide - Local Development build (v0.2.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

Resource Profile: OnconovaMolecularTumorBoardReview - Detailed Descriptions

Active as of 2026-03-18

Definitions for the onconova-molecular-tumor-board-review resource profile.

Guidance on how to interpret the contents of this table can be foundhere

0. Procedure
Definition

An action that is or was performed on or for a patient. This can be a physical intervention like an operation, or less invasive like long term services, counseling, or hypnotherapy.

ShortAn action that is being or was performed on a patient
Control0..*
Is Modifierfalse
Summaryfalse
Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
dom-6: A resource should have narrative for robust management (text.`div`.exists())
o-tub-req-1: The subject element is required and must be provided. (subject.exists())
o-tub-req-2: The performedDateTime element is required and must be provided. (performedDateTime.exists() and performedDateTime.hasValue())
2. Procedure.implicitRules
Definition

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

ShortA set of rules under which this content was created
Comments

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.

Control0..1
Typeuri
Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
4. Procedure.extension
Definition

An Extension


May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

ShortExtensionAdditional content defined by implementations
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control0..*
TypeExtension
Is Modifierfalse
Summaryfalse
Alternate Namesextensions, user content
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
SlicingThis element introduces a set of slices on Procedure.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • value @ url
  • 6. Procedure.extension:therapeuticRecommendation
    Slice NametherapeuticRecommendation
    Definition

    A therapeutic recommendation or follow-up action resulting from a molecular tumor board review.

    ShortTherapeutic recommendation(s)
    Control0..*
    This element is affected by the following invariants: ele-1
    TypeExtension(Molecular Tumor Board Therapeutic Recommendation) (Complex Extension)
    Is Modifierfalse
    Must Supporttrue
    Obligations
      ObligationsActor
      SHALL:populate-if-knownCreator (Onconova)
      SHOULD:persistConsumer (Onconova)
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      tumor-board-therapeutic-recommendation-1: Either clinical trial or medication SHALL be present (extension('clinicalTrial').exists() or extension('medication').exists())
      8. Procedure.extension:molecularComparison
      Slice NamemolecularComparison
      Definition

      A comparison of molecular findings discussed during the molecular tumor board review.

      ShortMolecular comparison(s)
      Control0..1
      This element is affected by the following invariants: ele-1
      TypeExtension(Molecular Tumor Board Molecular Comparison) (Complex Extension)
      Is Modifierfalse
      Must Supporttrue
      Obligations
        ObligationsActor
        SHALL:populate-if-knownCreator (Onconova)
        SHOULD:persistConsumer (Onconova)
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        10. Procedure.extension:cupCharacterization
        Slice NamecupCharacterization
        Definition

        A characterization of the tumor board review focused on cancer of unknown primary (CUP) origin.

        ShortCUP characterization(s)
        Control0..1
        This element is affected by the following invariants: ele-1
        TypeExtension(Molecular Tumor Board CUP Characterization) (Complex Extension)
        Is Modifierfalse
        Must Supporttrue
        Obligations
          ObligationsActor
          SHALL:populate-if-knownCreator (Onconova)
          SHOULD:persistConsumer (Onconova)
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
          12. Procedure.modifierExtension
          Definition

          May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

          ShortExtensions that cannot be ignored
          Comments

          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

          Control0..*
          TypeExtension
          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
          Summaryfalse
          Requirements

          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

          Alternate Namesextensions, user content
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
          14. Procedure.status
          Definition

          A code specifying the state of the procedure. Generally, this will be the in-progress or completed state.

          Shortpreparation | in-progress | not-done | on-hold | stopped | completed | entered-in-error | unknown
          Comments

          The "unknown" code is not to be used to convey other statuses. The "unknown" code should be used when one of the statuses applies, but the authoring system doesn't know the current state of the procedure.

          This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

          Control1..1
          BindingThe codes SHALL be taken from EventStatushttp://hl7.org/fhir/ValueSet/event-status|4.0.1
          (required to http://hl7.org/fhir/ValueSet/event-status|4.0.1)

          A code specifying the state of the procedure.

          Typecode
          Is Modifiertrue because This element is labelled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          16. Procedure.category
          Definition

          A code that classifies the procedure for searching, sorting and display purposes (e.g. "Surgical Procedure").

          ShortClassification of the procedure
          Control0..1
          BindingFor example codes, see ProcedureCategoryCodes(SNOMEDCT)http://hl7.org/fhir/ValueSet/procedure-category|4.0.1
          (example to http://hl7.org/fhir/ValueSet/procedure-category|4.0.1)

          A code that classifies a procedure for searching, sorting and display purposes.

          TypeCodeableConcept
          Is Modifierfalse
          Summarytrue
          Pattern Value{
            "coding" : [{
              "system" : "http://snomed.info/sct",
              "code" : "103693007",
              "display" : "Diagnostic procedure"
            }]
          }
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          18. Procedure.code
          Definition

          The specific procedure that is performed. Use text if the exact nature of the procedure cannot be coded (e.g. "Laparoscopic Appendectomy").

          ShortIdentification of the procedure
          Control0..1
          BindingFor example codes, see ProcedureCodes(SNOMEDCT)http://hl7.org/fhir/ValueSet/procedure-code|4.0.1
          (example to http://hl7.org/fhir/ValueSet/procedure-code|4.0.1)

          A code to identify a specific procedure .

          TypeCodeableConcept
          Is Modifierfalse
          Summarytrue
          Requirements

          0..1 to account for primarily narrative only resources.

          Alternate Namestype
          Pattern Value{
            "coding" : [{
              "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
              "code" : "C93304",
              "display" : "Tumor Board Review"
            }]
          }
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          20. Procedure.code.extension:specialization
          Slice Namespecialization
          Definition

          The specialization or focus area of the tumor board conducting the review, such as hematologic malignancies or solid tumors.

          ShortTumor Board Specialization
          Control0..1
          TypeExtension(Tumor Board Specialization) (Extension Type: CodeableConcept)
          Is Modifierfalse
          Must Supporttrue
          Obligations
            ObligationsActorSource
            SHALL:populate-if-knownCreator (Onconova)from Tumor Board Review Profile
            MAY:persistConsumer (Onconova)from Tumor Board Review Profile
            Summaryfalse
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            22. Procedure.code.extension:specialization.extension
            Definition

            An Extension


            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

            ShortExtensionAdditional content defined by implementations
            Comments

            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

            Control0..0*
            TypeExtension
            Is Modifierfalse
            Summaryfalse
            Alternate Namesextensions, user content
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            SlicingThis element introduces a set of slices on Procedure.code.extension.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
            • value @ url
            • 24. Procedure.code.extension:specialization.url
              Definition

              Source of the definition for the extension code - a logical name or a URL.

              Shortidentifies the meaning of the extension
              Comments

              The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

              Control1..1
              Typeuri
              Is Modifierfalse
              XML FormatIn the XML format, this property is represented as an attribute.
              Summaryfalse
              Fixed Valuehttp://onconova.github.io/fhir/StructureDefinition/onconova-ext-tumor-board-specialization
              26. Procedure.code.extension:specialization.value[x]
              Definition

              Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).

              ShortValue of extension
              Control0..1
              TypeCodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
              Is Modifierfalse
              Summaryfalse
              Pattern Value{
                "coding" : [{
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C20826",
                  "display" : "Molecular Diagnosis"
                }]
              }
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              28. Procedure.subject
              Definition

              The person, animal or group on which the procedure was performed.

              ShortWho the procedure was performed on
              Control1..1
              TypeReference(Cancer Patient Profile, Patient, Group)
              Is Modifierfalse
              Must Supporttrue
              Obligations
                ObligationsActorSource
                SHALL:populateCreator (Onconova)from Tumor Board Review Profile
                SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                Summarytrue
                Alternate Namespatient
                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                30. Procedure.performed[x]
                Definition

                Estimated or actual date, date-time, period, or age when the procedure was performed. Allows a period to support complex procedures that span more than one date, and also allows for the length of the procedure to be captured.

                ShortWhen the procedure was performed
                Comments

                Age is generally used when the patient reports an age at which the procedure was performed. Range is generally used when the patient reports an age range when the procedure was performed, such as sometime between 20-25 years old. dateTime supports a range of precision due to some procedures being reported as past procedures that might not have millisecond precision while other procedures performed and documented during the encounter might have more precise UTC timestamps with timezone.

                Control10..1
                TypedateTime, string, Period, Range, Age
                [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                Is Modifierfalse
                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                Must Supporttrue
                Summarytrue
                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                SlicingThis element introduces a set of slices on Procedure.performed[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
                • type @ $this
                • 32. Procedure.performed[x]:performedDateTime
                  Slice NameperformedDateTime
                  Definition

                  Estimated or actual date, date-time, period, or age when the procedure was performed. Allows a period to support complex procedures that span more than one date, and also allows for the length of the procedure to be captured.

                  ShortThe date when the tumor board review was performedWhen the procedure was performed
                  Comments

                  Age is generally used when the patient reports an age at which the procedure was performed. Range is generally used when the patient reports an age range when the procedure was performed, such as sometime between 20-25 years old. dateTime supports a range of precision due to some procedures being reported as past procedures that might not have millisecond precision while other procedures performed and documented during the encounter might have more precise UTC timestamps with timezone.

                  Control0..1
                  TypedateTime, string, Period, Range, Age
                  [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                  Is Modifierfalse
                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                  Obligations
                    ObligationsActorSource
                    SHALL:populateCreator (Onconova)from Tumor Board Review Profile
                    SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                    SHALL:populateCreator (Onconova)from Tumor Board Review Profile
                    SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                    Summarytrue
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    34. Procedure.reasonReference
                    Definition

                    The justification of why the procedure was performed.

                    ShortThe condition(s) that motivated the tumor boardThe justification that the procedure was performed
                    Comments

                    It is possible for a procedure to be a reason (such as C-Section) for another procedure (such as an epidural). Other examples include endoscopy for dilatation and biopsy (a combination of diagnostic and therapeutic use). Use Procedure.reasonCode when a code sufficiently describes the reason. Use Procedure.reasonReference when referencing a resource, which allows more information to be conveyed, such as onset date. Procedure.reasonCode and Procedure.reasonReference are not meant to be duplicative. For a single reason, either Procedure.reasonCode or Procedure.reasonReference can be used. Procedure.reasonCode may be a summary code, or Procedure.reasonReference may be used to reference a very precise definition of the reason using Condition | Observation | Procedure | DiagnosticReport | DocumentReference. Both Procedure.reasonCode and Procedure.reasonReference can be used if they are describing different reasons for the procedure.

                    Control10..*
                    TypeReference(Primary Cancer Condition Profile, Secondary Cancer Condition Profile, Condition, Observation, Procedure, DiagnosticReport, DocumentReference)
                    Is Modifierfalse
                    Must Supporttrue
                    Must Support TypesNo must-support rules about the choice of types/profiles
                    Summarytrue
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    36. Procedure.followUp
                    Definition

                    Any recommendations or follow-up actions resulting from the tumor board.


                    If the procedure required specific follow up - e.g. removal of sutures. The follow up may be represented as a simple note or could potentially be more complex, in which case the CarePlan resource can be used.

                    ShortTumor Board RecommendationInstructions for follow up
                    Control0..*
                    BindingThe codes SHALL be taken from For example codes, see Tumor Board Recommendations Value Sethttp://hl7.org/fhir/ValueSet/procedure-followup|4.0.1
                    (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-tumor-board-recommendations)
                    TypeCodeableConcept
                    Is Modifierfalse
                    Must Supporttrue
                    Obligations
                      ObligationsActorSource
                      SHALL:populate-if-knownCreator (Onconova)from Tumor Board Review Profile
                      SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                      Summaryfalse
                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))

                      Guidance on how to interpret the contents of this table can be foundhere

                      0. Procedure
                      Invariantso-tub-req-1: The subject element is required and must be provided. (subject.exists())
                      o-tub-req-2: The performedDateTime element is required and must be provided. (performedDateTime.exists() and performedDateTime.hasValue())
                      2. Procedure.extension
                      SlicingThis element introduces a set of slices on Procedure.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                      • value @ url
                      • 4. Procedure.extension:therapeuticRecommendation
                        Slice NametherapeuticRecommendation
                        ShortTherapeutic recommendation(s)
                        Control0..*
                        TypeExtension(Molecular Tumor Board Therapeutic Recommendation) (Complex Extension)
                        Must Supporttrue
                        Obligations
                          ObligationsActor
                          SHALL:populate-if-knownCreator (Onconova)
                          SHOULD:persistConsumer (Onconova)
                          6. Procedure.extension:molecularComparison
                          Slice NamemolecularComparison
                          ShortMolecular comparison(s)
                          Control0..1
                          TypeExtension(Molecular Tumor Board Molecular Comparison) (Complex Extension)
                          Must Supporttrue
                          Obligations
                            ObligationsActor
                            SHALL:populate-if-knownCreator (Onconova)
                            SHOULD:persistConsumer (Onconova)
                            8. Procedure.extension:cupCharacterization
                            Slice NamecupCharacterization
                            ShortCUP characterization(s)
                            Control0..1
                            TypeExtension(Molecular Tumor Board CUP Characterization) (Complex Extension)
                            Must Supporttrue
                            Obligations
                              ObligationsActor
                              SHALL:populate-if-knownCreator (Onconova)
                              SHOULD:persistConsumer (Onconova)
                              10. Procedure.code
                              12. Procedure.code.extension:specialization
                              Slice Namespecialization
                              14. Procedure.code.extension:specialization.value[x]
                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                              Pattern Value{
                                "coding" : [{
                                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                                  "code" : "C20826",
                                  "display" : "Molecular Diagnosis"
                                }]
                              }

                              Guidance on how to interpret the contents of this table can be foundhere

                              0. Procedure
                              Definition

                              An action that is or was performed on or for a patient. This can be a physical intervention like an operation, or less invasive like long term services, counseling, or hypnotherapy.

                              ShortAn action that is being or was performed on a patient
                              Control0..*
                              Is Modifierfalse
                              Summaryfalse
                              Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
                              dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
                              dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
                              dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
                              dom-6: A resource should have narrative for robust management (text.`div`.exists())
                              o-tub-req-1: The subject element is required and must be provided. (subject.exists())
                              o-tub-req-2: The performedDateTime element is required and must be provided. (performedDateTime.exists() and performedDateTime.hasValue())
                              2. Procedure.id
                              Definition

                              The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

                              ShortLogical id of this artifact
                              Comments

                              The only time that a resource does not have an id is when it is being submitted to the server using a create operation.

                              Control0..1
                              Typeid
                              Is Modifierfalse
                              Summarytrue
                              4. Procedure.meta
                              Definition

                              The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

                              ShortMetadata about the resource
                              Control0..1
                              TypeMeta
                              Is Modifierfalse
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              6. Procedure.implicitRules
                              Definition

                              A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

                              ShortA set of rules under which this content was created
                              Comments

                              Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.

                              Control0..1
                              Typeuri
                              Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              8. Procedure.language
                              Definition

                              The base language in which the resource is written.

                              ShortLanguage of the resource content
                              Comments

                              Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

                              Control0..1
                              BindingThe codes SHOULD be taken from CommonLanguages
                              (preferred to http://hl7.org/fhir/ValueSet/languages|4.0.1)

                              A human language.

                              Additional BindingsPurpose
                              AllLanguagesMax Binding
                              Typecode
                              Is Modifierfalse
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summaryfalse
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              10. Procedure.text
                              Definition

                              A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

                              ShortText summary of the resource, for human interpretation
                              Comments

                              Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.

                              Control0..1
                              TypeNarrative
                              Is Modifierfalse
                              Summaryfalse
                              Alternate Namesnarrative, html, xhtml, display
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              12. Procedure.contained
                              Definition

                              These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.

                              ShortContained, inline Resources
                              Comments

                              This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.

                              Control0..*
                              TypeResource
                              Is Modifierfalse
                              Summaryfalse
                              Alternate Namesinline resources, anonymous resources, contained resources
                              14. Procedure.extension
                              Definition

                              An Extension

                              ShortExtension
                              Control0..*
                              TypeExtension
                              Is Modifierfalse
                              Summaryfalse
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                              SlicingThis element introduces a set of slices on Procedure.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                              • value @ url
                              • 16. Procedure.extension:therapeuticRecommendation
                                Slice NametherapeuticRecommendation
                                Definition

                                A therapeutic recommendation or follow-up action resulting from a molecular tumor board review.

                                ShortTherapeutic recommendation(s)
                                Control0..*
                                This element is affected by the following invariants: ele-1
                                TypeExtension(Molecular Tumor Board Therapeutic Recommendation) (Complex Extension)
                                Is Modifierfalse
                                Must Supporttrue
                                Obligations
                                  ObligationsActor
                                  SHALL:populate-if-knownCreator (Onconova)
                                  SHOULD:persistConsumer (Onconova)
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  tumor-board-therapeutic-recommendation-1: Either clinical trial or medication SHALL be present (extension('clinicalTrial').exists() or extension('medication').exists())
                                  18. Procedure.extension:molecularComparison
                                  Slice NamemolecularComparison
                                  Definition

                                  A comparison of molecular findings discussed during the molecular tumor board review.

                                  ShortMolecular comparison(s)
                                  Control0..1
                                  This element is affected by the following invariants: ele-1
                                  TypeExtension(Molecular Tumor Board Molecular Comparison) (Complex Extension)
                                  Is Modifierfalse
                                  Must Supporttrue
                                  Obligations
                                    ObligationsActor
                                    SHALL:populate-if-knownCreator (Onconova)
                                    SHOULD:persistConsumer (Onconova)
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                    20. Procedure.extension:cupCharacterization
                                    Slice NamecupCharacterization
                                    Definition

                                    A characterization of the tumor board review focused on cancer of unknown primary (CUP) origin.

                                    ShortCUP characterization(s)
                                    Control0..1
                                    This element is affected by the following invariants: ele-1
                                    TypeExtension(Molecular Tumor Board CUP Characterization) (Complex Extension)
                                    Is Modifierfalse
                                    Must Supporttrue
                                    Obligations
                                      ObligationsActor
                                      SHALL:populate-if-knownCreator (Onconova)
                                      SHOULD:persistConsumer (Onconova)
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                      22. Procedure.modifierExtension
                                      Definition

                                      May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                      ShortExtensions that cannot be ignored
                                      Comments

                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                      Control0..*
                                      TypeExtension
                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
                                      Summaryfalse
                                      Requirements

                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                      Alternate Namesextensions, user content
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                      24. Procedure.identifier
                                      Definition

                                      Business identifiers assigned to this procedure by the performer or other systems which remain constant as the resource is updated and is propagated from server to server.

                                      ShortExternal Identifiers for this procedure
                                      Comments

                                      This is a business identifier, not a resource identifier (see discussion). It is best practice for the identifier to only appear on a single resource instance, however business practices may occasionally dictate that multiple resource instances with the same identifier can exist - possibly even with different resource types. For example, multiple Patient and Person resource instances might share the same social insurance number.

                                      NoteThis is a business identifier, not a resource identifier (see discussion)
                                      Control0..*
                                      TypeIdentifier
                                      Is Modifierfalse
                                      Summarytrue
                                      Requirements

                                      Allows identification of the procedure as it is known by various participating systems and in a way that remains consistent across servers.

                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      26. Procedure.instantiatesCanonical
                                      Definition

                                      The URL pointing to a FHIR-defined protocol, guideline, order set or other definition that is adhered to in whole or in part by this Procedure.

                                      ShortInstantiates FHIR protocol or definition
                                      Control0..*
                                      Typecanonical(PlanDefinition, ActivityDefinition, Measure, OperationDefinition, Questionnaire)
                                      Is Modifierfalse
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      28. Procedure.instantiatesUri
                                      Definition

                                      The URL pointing to an externally maintained protocol, guideline, order set or other definition that is adhered to in whole or in part by this Procedure.

                                      ShortInstantiates external protocol or definition
                                      Comments

                                      This might be an HTML page, PDF, etc. or could just be a non-resolvable URI identifier.

                                      Control0..*
                                      Typeuri
                                      Is Modifierfalse
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      30. Procedure.basedOn
                                      Definition

                                      Not used in this profile

                                      ShortNot used in this profile
                                      Control0..*
                                      TypeReference(CarePlan, ServiceRequest)
                                      Is Modifierfalse
                                      Summarytrue
                                      Alternate Namesfulfills
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      32. Procedure.partOf
                                      Definition

                                      A larger event of which this particular procedure is a component or step.

                                      ShortPart of referenced event
                                      Comments

                                      The MedicationAdministration resource has a partOf reference to Procedure, but this is not a circular reference. For example, the anesthesia MedicationAdministration is part of the surgical Procedure (MedicationAdministration.partOf = Procedure). For example, the procedure to insert the IV port for an IV medication administration is part of the medication administration (Procedure.partOf = MedicationAdministration).

                                      Control0..*
                                      TypeReference(Procedure, Observation, MedicationAdministration)
                                      Is Modifierfalse
                                      Summarytrue
                                      Alternate Namescontainer
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      34. Procedure.status
                                      Definition

                                      A code specifying the state of the procedure. Generally, this will be the in-progress or completed state.

                                      Shortpreparation | in-progress | not-done | on-hold | stopped | completed | entered-in-error | unknown
                                      Comments

                                      The "unknown" code is not to be used to convey other statuses. The "unknown" code should be used when one of the statuses applies, but the authoring system doesn't know the current state of the procedure.

                                      This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

                                      Control1..1
                                      BindingThe codes SHALL be taken from EventStatus
                                      (required to http://hl7.org/fhir/ValueSet/event-status|4.0.1)

                                      A code specifying the state of the procedure.

                                      Typecode
                                      Is Modifiertrue because This element is labelled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      36. Procedure.statusReason
                                      Definition

                                      Captures the reason for the current state of the procedure.

                                      ShortReason for current status
                                      Comments

                                      This is generally only used for "exception" statuses such as "not-done", "suspended" or "aborted". The reason for performing the event at all is captured in reasonCode, not here.

                                      Control0..1
                                      BindingFor example codes, see ProcedureNotPerformedReason(SNOMED-CT)
                                      (example to http://hl7.org/fhir/ValueSet/procedure-not-performed-reason|4.0.1)

                                      A code that identifies the reason a procedure was not performed.

                                      TypeCodeableConcept
                                      Is Modifierfalse
                                      Summarytrue
                                      Alternate NamesSuspended Reason, Cancelled Reason
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      38. Procedure.category
                                      Definition

                                      A code that classifies the procedure for searching, sorting and display purposes (e.g. "Surgical Procedure").

                                      ShortClassification of the procedure
                                      Control0..1
                                      BindingFor example codes, see ProcedureCategoryCodes(SNOMEDCT)
                                      (example to http://hl7.org/fhir/ValueSet/procedure-category|4.0.1)

                                      A code that classifies a procedure for searching, sorting and display purposes.

                                      TypeCodeableConcept
                                      Is Modifierfalse
                                      Summarytrue
                                      Pattern Value{
                                        "coding" : [{
                                          "system" : "http://snomed.info/sct",
                                          "code" : "103693007",
                                          "display" : "Diagnostic procedure"
                                        }]
                                      }
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      40. Procedure.code
                                      Definition

                                      The specific procedure that is performed. Use text if the exact nature of the procedure cannot be coded (e.g. "Laparoscopic Appendectomy").

                                      ShortIdentification of the procedure
                                      Control0..1
                                      BindingFor example codes, see ProcedureCodes(SNOMEDCT)
                                      (example to http://hl7.org/fhir/ValueSet/procedure-code|4.0.1)

                                      A code to identify a specific procedure .

                                      TypeCodeableConcept
                                      Is Modifierfalse
                                      Summarytrue
                                      Requirements

                                      0..1 to account for primarily narrative only resources.

                                      Alternate Namestype
                                      Pattern Value{
                                        "coding" : [{
                                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                                          "code" : "C93304",
                                          "display" : "Tumor Board Review"
                                        }]
                                      }
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      42. Procedure.code.id
                                      Definition

                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                      ShortUnique id for inter-element referencing
                                      Control0..1
                                      Typestring
                                      Is Modifierfalse
                                      XML FormatIn the XML format, this property is represented as an attribute.
                                      Summaryfalse
                                      44. Procedure.code.extension
                                      Definition

                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                      ShortAdditional content defined by implementations
                                      Comments

                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                      Control0..*
                                      TypeExtension
                                      Is Modifierfalse
                                      Summaryfalse
                                      Alternate Namesextensions, user content
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                      SlicingThis element introduces a set of slices on Procedure.code.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                      • value @ url
                                      • 46. Procedure.code.extension:specialization
                                        Slice Namespecialization
                                        Definition

                                        The specialization or focus area of the tumor board conducting the review, such as hematologic malignancies or solid tumors.

                                        ShortTumor Board Specialization
                                        Control0..1
                                        TypeExtension(Tumor Board Specialization) (Extension Type: CodeableConcept)
                                        Is Modifierfalse
                                        Must Supporttrue
                                        Obligations
                                          ObligationsActorSource
                                          SHALL:populate-if-knownCreator (Onconova)from Tumor Board Review Profile
                                          MAY:persistConsumer (Onconova)from Tumor Board Review Profile
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                          48. Procedure.code.extension:specialization.id
                                          Definition

                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                          ShortUnique id for inter-element referencing
                                          Control0..1
                                          Typestring
                                          Is Modifierfalse
                                          XML FormatIn the XML format, this property is represented as an attribute.
                                          Summaryfalse
                                          50. Procedure.code.extension:specialization.extension
                                          Definition

                                          An Extension

                                          ShortExtension
                                          Control0..0
                                          TypeExtension
                                          Is Modifierfalse
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                          SlicingThis element introduces a set of slices on Procedure.code.extension.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                          • value @ url
                                          • 52. Procedure.code.extension:specialization.url
                                            Definition

                                            Source of the definition for the extension code - a logical name or a URL.

                                            Shortidentifies the meaning of the extension
                                            Comments

                                            The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

                                            Control1..1
                                            Typeuri
                                            Is Modifierfalse
                                            XML FormatIn the XML format, this property is represented as an attribute.
                                            Summaryfalse
                                            Fixed Valuehttp://onconova.github.io/fhir/StructureDefinition/onconova-ext-tumor-board-specialization
                                            54. Procedure.code.extension:specialization.value[x]
                                            Definition

                                            Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).

                                            ShortValue of extension
                                            Control0..1
                                            TypeCodeableConcept
                                            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                            Is Modifierfalse
                                            Summaryfalse
                                            Pattern Value{
                                              "coding" : [{
                                                "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                                                "code" : "C20826",
                                                "display" : "Molecular Diagnosis"
                                              }]
                                            }
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            56. Procedure.code.coding
                                            Definition

                                            A reference to a code defined by a terminology system.

                                            ShortCode defined by a terminology system
                                            Comments

                                            Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

                                            Control0..*
                                            TypeCoding
                                            Is Modifierfalse
                                            Summarytrue
                                            Requirements

                                            Allows for alternative encodings within a code system, and translations to other code systems.

                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            58. Procedure.code.text
                                            Definition

                                            A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.

                                            ShortPlain text representation of the concept
                                            Comments

                                            Very often the text is the same as a displayName of one of the codings.

                                            Control0..1
                                            Typestring
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            Requirements

                                            The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            60. Procedure.subject
                                            Definition

                                            The person, animal or group on which the procedure was performed.

                                            ShortWho the procedure was performed on
                                            Control1..1
                                            TypeReference(Cancer Patient Profile)
                                            Is Modifierfalse
                                            Must Supporttrue
                                            Obligations
                                              ObligationsActorSource
                                              SHALL:populateCreator (Onconova)from Tumor Board Review Profile
                                              SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                                              Summarytrue
                                              Alternate Namespatient
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              62. Procedure.encounter
                                              Definition

                                              The Encounter during which this Procedure was created or performed or to which the creation of this record is tightly associated.

                                              ShortEncounter created as part of
                                              Comments

                                              This will typically be the encounter the event occurred within, but some activities may be initiated prior to or after the official completion of an encounter but still be tied to the context of the encounter.

                                              Control0..1
                                              TypeReference(Encounter)
                                              Is Modifierfalse
                                              Summarytrue
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              64. Procedure.performed[x]
                                              Definition

                                              Estimated or actual date, date-time, period, or age when the procedure was performed. Allows a period to support complex procedures that span more than one date, and also allows for the length of the procedure to be captured.

                                              ShortWhen the procedure was performed
                                              Comments

                                              Age is generally used when the patient reports an age at which the procedure was performed. Range is generally used when the patient reports an age range when the procedure was performed, such as sometime between 20-25 years old. dateTime supports a range of precision due to some procedures being reported as past procedures that might not have millisecond precision while other procedures performed and documented during the encounter might have more precise UTC timestamps with timezone.

                                              Control1..1
                                              TypedateTime
                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                              Is Modifierfalse
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Must Supporttrue
                                              Summarytrue
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              SlicingThis element introduces a set of slices on Procedure.performed[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
                                              • type @ $this
                                              • 66. Procedure.performed[x]:performedDateTime
                                                Slice NameperformedDateTime
                                                Definition

                                                Estimated or actual date, date-time, period, or age when the procedure was performed. Allows a period to support complex procedures that span more than one date, and also allows for the length of the procedure to be captured.

                                                ShortThe date when the tumor board review was performed
                                                Comments

                                                Age is generally used when the patient reports an age at which the procedure was performed. Range is generally used when the patient reports an age range when the procedure was performed, such as sometime between 20-25 years old. dateTime supports a range of precision due to some procedures being reported as past procedures that might not have millisecond precision while other procedures performed and documented during the encounter might have more precise UTC timestamps with timezone.

                                                Control0..1
                                                TypedateTime
                                                [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                Is Modifierfalse
                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                Obligations
                                                  ObligationsActorSource
                                                  SHALL:populateCreator (Onconova)from Tumor Board Review Profile
                                                  SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                                                  SHALL:populateCreator (Onconova)from Tumor Board Review Profile
                                                  SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  68. Procedure.recorder
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Control0..1
                                                  TypeReference(Patient, RelatedPerson, Practitioner, PractitionerRole)
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  70. Procedure.asserter
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Control0..1
                                                  TypeReference(Patient, RelatedPerson, Practitioner, PractitionerRole)
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  72. Procedure.performer
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Control0..*
                                                  TypeBackboneElement
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  74. Procedure.performer.id
                                                  Definition

                                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                  ShortUnique id for inter-element referencing
                                                  Control0..1
                                                  Typestring
                                                  Is Modifierfalse
                                                  XML FormatIn the XML format, this property is represented as an attribute.
                                                  Summaryfalse
                                                  76. Procedure.performer.extension
                                                  Definition

                                                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                  ShortAdditional content defined by implementations
                                                  Comments

                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                  Control0..*
                                                  TypeExtension
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Alternate Namesextensions, user content
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  78. Procedure.performer.modifierExtension
                                                  Definition

                                                  May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                  ShortExtensions that cannot be ignored even if unrecognized
                                                  Comments

                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                  Control0..*
                                                  TypeExtension
                                                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                  Summarytrue
                                                  Requirements

                                                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                  Alternate Namesextensions, user content, modifiers
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  80. Procedure.performer.function
                                                  Definition

                                                  Distinguishes the type of involvement of the performer in the procedure. For example, surgeon, anaesthetist, endoscopist.

                                                  ShortType of performance
                                                  Control0..1
                                                  BindingFor example codes, see ProcedurePerformerRoleCodes
                                                  (example to http://hl7.org/fhir/ValueSet/performer-role|4.0.1)

                                                  A code that identifies the role of a performer of the procedure.

                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Requirements

                                                  Allows disambiguation of the types of involvement of different performers.

                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  82. Procedure.performer.actor
                                                  Definition

                                                  The practitioner who was involved in the procedure.

                                                  ShortThe reference to the practitioner
                                                  Control1..1
                                                  TypeReference(Practitioner, PractitionerRole, Organization, Patient, RelatedPerson, Device)
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Requirements

                                                  A reference to Device supports use cases, such as pacemakers.

                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  84. Procedure.performer.onBehalfOf
                                                  Definition

                                                  The organization the device or practitioner was acting on behalf of.

                                                  ShortOrganization the device or practitioner was acting for
                                                  Control0..1
                                                  TypeReference(Organization)
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Requirements

                                                  Practitioners and Devices can be associated with multiple organizations. This element indicates which organization they were acting on behalf of when performing the action.

                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  86. Procedure.location
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Control0..1
                                                  TypeReference(Location)
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Requirements

                                                  Ties a procedure to where the records are likely kept.

                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  88. Procedure.reasonCode
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Comments

                                                  Use Procedure.reasonCode when a code sufficiently describes the reason. Use Procedure.reasonReference when referencing a resource, which allows more information to be conveyed, such as onset date. Procedure.reasonCode and Procedure.reasonReference are not meant to be duplicative. For a single reason, either Procedure.reasonCode or Procedure.reasonReference can be used. Procedure.reasonCode may be a summary code, or Procedure.reasonReference may be used to reference a very precise definition of the reason using Condition | Observation | Procedure | DiagnosticReport | DocumentReference. Both Procedure.reasonCode and Procedure.reasonReference can be used if they are describing different reasons for the procedure.

                                                  Control0..*
                                                  BindingFor example codes, see ProcedureReasonCodes
                                                  (example to http://hl7.org/fhir/ValueSet/procedure-reason|4.0.1)

                                                  A code that identifies the reason a procedure is required.

                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  90. Procedure.reasonReference
                                                  Definition

                                                  The justification of why the procedure was performed.

                                                  ShortThe condition(s) that motivated the tumor board
                                                  Comments

                                                  It is possible for a procedure to be a reason (such as C-Section) for another procedure (such as an epidural). Other examples include endoscopy for dilatation and biopsy (a combination of diagnostic and therapeutic use). Use Procedure.reasonCode when a code sufficiently describes the reason. Use Procedure.reasonReference when referencing a resource, which allows more information to be conveyed, such as onset date. Procedure.reasonCode and Procedure.reasonReference are not meant to be duplicative. For a single reason, either Procedure.reasonCode or Procedure.reasonReference can be used. Procedure.reasonCode may be a summary code, or Procedure.reasonReference may be used to reference a very precise definition of the reason using Condition | Observation | Procedure | DiagnosticReport | DocumentReference. Both Procedure.reasonCode and Procedure.reasonReference can be used if they are describing different reasons for the procedure.

                                                  Control1..*
                                                  TypeReference(Primary Cancer Condition Profile, Secondary Cancer Condition Profile)
                                                  Is Modifierfalse
                                                  Must Supporttrue
                                                  Must Support TypesNo must-support rules about the choice of types/profiles
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  92. Procedure.bodySite
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Comments

                                                  If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension procedure-targetbodystructure.

                                                  Control0..*
                                                  BindingFor example codes, see SNOMEDCTBodyStructures
                                                  (example to http://hl7.org/fhir/ValueSet/body-site|4.0.1)

                                                  Codes describing anatomical locations. May include laterality.

                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  94. Procedure.outcome
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Comments

                                                  If outcome contains narrative text only, it can be captured using the CodeableConcept.text.

                                                  Control0..1
                                                  BindingFor example codes, see ProcedureOutcomeCodes(SNOMEDCT)
                                                  (example to http://hl7.org/fhir/ValueSet/procedure-outcome|4.0.1)

                                                  An outcome of a procedure - whether it was resolved or otherwise.

                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  96. Procedure.report
                                                  Definition

                                                  This could be a histology result, pathology report, surgical report, etc.

                                                  ShortAny report resulting from the procedure
                                                  Comments

                                                  There could potentially be multiple reports - e.g. if this was a procedure which took multiple biopsies resulting in a number of anatomical pathology reports.

                                                  Control0..*
                                                  TypeReference(DiagnosticReport, DocumentReference, Composition)
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  98. Procedure.complication
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Comments

                                                  If complications are only expressed by the narrative text, they can be captured using the CodeableConcept.text.

                                                  Control0..*
                                                  BindingFor example codes, see Condition/Problem/DiagnosisCodes
                                                  (example to http://hl7.org/fhir/ValueSet/condition-code|4.0.1)

                                                  Codes describing complications that resulted from a procedure.

                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  100. Procedure.complicationDetail
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  Control0..*
                                                  TypeReference(Condition)
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Requirements

                                                  This is used to document a condition that is a result of the procedure, not the condition that was the reason for the procedure.

                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  102. Procedure.followUp
                                                  Definition

                                                  Any recommendations or follow-up actions resulting from the tumor board.

                                                  ShortTumor Board Recommendation
                                                  Control0..*
                                                  BindingThe codes SHALL be taken from Tumor Board Recommendations Value Set
                                                  (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-tumor-board-recommendations)
                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Must Supporttrue
                                                  Obligations
                                                    ObligationsActorSource
                                                    SHALL:populate-if-knownCreator (Onconova)from Tumor Board Review Profile
                                                    SHOULD:persistConsumer (Onconova)from Tumor Board Review Profile
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    104. Procedure.note
                                                    Definition

                                                    Any other notes and comments about the procedure.

                                                    ShortAdditional information about the procedure
                                                    Control0..*
                                                    TypeAnnotation
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    106. Procedure.focalDevice
                                                    Definition

                                                    A device that is implanted, removed or otherwise manipulated (calibration, battery replacement, fitting a prosthesis, attaching a wound-vac, etc.) as a focal portion of the Procedure.

                                                    ShortManipulated, implanted, or removed device
                                                    Control0..*
                                                    TypeBackboneElement
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    108. Procedure.focalDevice.id
                                                    Definition

                                                    Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                    ShortUnique id for inter-element referencing
                                                    Control0..1
                                                    Typestring
                                                    Is Modifierfalse
                                                    XML FormatIn the XML format, this property is represented as an attribute.
                                                    Summaryfalse
                                                    110. Procedure.focalDevice.extension
                                                    Definition

                                                    May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                    ShortAdditional content defined by implementations
                                                    Comments

                                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                    Control0..*
                                                    TypeExtension
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Alternate Namesextensions, user content
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    112. Procedure.focalDevice.modifierExtension
                                                    Definition

                                                    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                    ShortExtensions that cannot be ignored even if unrecognized
                                                    Comments

                                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                    Control0..*
                                                    TypeExtension
                                                    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                    Summarytrue
                                                    Requirements

                                                    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                    Alternate Namesextensions, user content, modifiers
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    114. Procedure.focalDevice.action
                                                    Definition

                                                    The kind of change that happened to the device during the procedure.

                                                    ShortKind of change to device
                                                    Control0..1
                                                    BindingThe codes SHOULD be taken from ProcedureDeviceActionCodes
                                                    (preferred to http://hl7.org/fhir/ValueSet/device-action|4.0.1)

                                                    A kind of change that happened to the device during the procedure.

                                                    TypeCodeableConcept
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    116. Procedure.focalDevice.manipulated
                                                    Definition

                                                    The device that was manipulated (changed) during the procedure.

                                                    ShortDevice that was changed
                                                    Control1..1
                                                    TypeReference(Device)
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    118. Procedure.usedReference
                                                    Definition

                                                    Identifies medications, devices and any other substance used as part of the procedure.

                                                    ShortItems used during procedure
                                                    Comments

                                                    For devices actually implanted or removed, use Procedure.device.

                                                    Control0..*
                                                    TypeReference(Device, Medication, Substance)
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Requirements

                                                    Used for tracking contamination, etc.

                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    120. Procedure.usedCode
                                                    Definition

                                                    Identifies coded items that were used as part of the procedure.

                                                    ShortCoded items used during the procedure
                                                    Comments

                                                    For devices actually implanted or removed, use Procedure.device.

                                                    Control0..*
                                                    BindingFor example codes, see FHIRDeviceTypes
                                                    (example to http://hl7.org/fhir/ValueSet/device-kind|4.0.1)

                                                    Codes describing items used during a procedure.

                                                    TypeCodeableConcept
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))