Onconova Implementation Guide
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CapabilityStatement: Onconova FHIR REST Capability Statement

Official URL: http://onconova.github.io/fhir/CapabilityStatement/onconova-capability-statement Version: 0.2.0
Draft as of 2025-09-25 Computable Name: OnconovaCapabilityStatement

Supports the retrieval of the mCODE Patient Bundle containing all relevant mCODE resources (provided by Onconova) for a given patient. It also supports CRUD interactions on all Onconova profiles defined in this Implementation Guide.

Raw OpenAPI-Swagger Definition file | Download

Onconova FHIR REST Capability Statement

  • Implementation Guide Version: 0.2.0
  • FHIR Version: 4.0.1
  • Supported Formats: json
  • Published on: 2025-09-25
  • Published by: Onconova

Note to Implementers: FHIR Capabilities

Any FHIR capability may be 'allowed' by the system unless explicitly marked as 'SHALL NOT'. A few items are marked as MAY in the Implementation Guide to highlight their potential relevance to the use case.

This CapabilityStatement imports the CapabilityStatement mCODE Data Sender: Get Bundle for a Patientversion: 4.0.0)

SHALL Support the Following Implementation Guides

FHIR RESTful Capabilities

Mode: server

As an mCODE-compliant server, the Onconova FHIR server SHALL:

  1. Support all profiles defined in this Implementation Guide.
  2. Implement the RESTful behavior according to the FHIR specification.
  3. Return the following response classes:
    • (Status 400): invalid parameter
    • (Status 401/4xx): unauthorized request
    • (Status 403): insufficient scope
    • (Status 404): unknown resource
    • (Status 410): deleted resource.
  4. Support json source formats for all mCODE interactions.
  5. Identify the mCODE profiles supported as part of the FHIR meta.profile attribute for each instance.
  6. Support the searchParameters on each profile individually and in combination.

The Onconova FHIR server does NOT:

1. Support xml source formats for mCODE interactions.
Security
  1. See the General Security Considerations section for requirements and recommendations.
  2. A server SHALL reject any unauthorized requests by returning an HTTP 401 unauthorized response code.
Summary of System-wide Operations
ConformanceOperationDocumentation
SHALL$mcode-patient-bundle

Capabilities by Resource/Profile

Summary

The summary table lists the resources that are part of this configuration, and for each resource it lists:

  • The relevant profiles (if any)
  • The interactions supported by each resource (Read, Search, Update, and Create, are always shown, while VRead, Patch, Delete, History on Instance, or History on Type are only present if at least one of the resources has support for them.
  • The required, recommended, and some optional search parameters (if any).
  • The linked resources enabled for _include
  • The other resources enabled for _revinclude
  • The operations on the resource (if any)
Resource TypeProfileRSUCDSearches_include_revincludeOperations
Patienthttp://onconova.github.io/fhir/StructureDefinition/onconova-cancer-patient|0.2.0yyyy
ConditionSupported Profiles
  Primary Cancer Condition Profileversion: 0.2.0)
  Secondary Cancer Condition Profileversion: 0.2.0)		yyyy
ObservationSupported Profiles
  Tumor Marker Profileversion: 0.2.0)
  Cancer Risk Assessment Profileversion: 0.2.0)
  Genomic Variant Profileversion: 0.2.0)
  Tumor Mutational Burden Profileversion: 0.2.0)
  Microsatellite Instability Profileversion: 0.2.0)
  Loss of Heterozygosity Profileversion: 0.2.0)
  Homologous Recombination Deficiency Profileversion: 0.2.0)
  Tumor Neoantigen Burden Profileversion: 0.2.0)
  Aneuploid Score Profileversion: 0.2.0)
  Cancer Stageversion: 0.2.0)
  TNM Stage Groupversion: 0.2.0)
  Comorbidities Profileversion: 0.2.0)
  Lifestyle Profileversion: 0.2.0)
  Karnofsky Performance Status Profileversion: 0.2.0)
  ECOG Performance Status Profileversion: 0.2.0)
  Imaging Disease Status Profileversion: 0.2.0)
  TNM Primary Tumor Categoryversion: 0.2.0)
  TNM Distant Metastases Categoryversion: 0.2.0)
  TNM Regional Nodes Categoryversion: 0.2.0)
  TNM Lymphatic Invasion Categoryversion: 0.2.0)
  TNM Perineural Invasion Categoryversion: 0.2.0)
  TNM Residual Tumor Categoryversion: 0.2.0)
  TNM Grade Categoryversion: 0.2.0)
  Serum Tumor Marker Level Categoryversion: 0.2.0)
  Venous Invasion Categoryversion: 0.2.0)
  Observation Body Height Profileversion: 4.0.1)
  Observation Body Weight Profileversion: 4.0.1)
  Observation Body Temperature Profileversion: 4.0.1)
  Observation Body Mass Index Profileversion: 4.0.1)
  Observation Blood Pressure Profileversion: 4.0.1)		yyyy
ProcedureSupported Profiles
  Surgical Procedure Profileversion: 0.2.0)
  Radiotherapy Summary Profileversion: 0.2.0)
  Tumor Board Reviewversion: 0.2.0)
  Molecular Tumor Board Reviewversion: 0.2.0)		yyyy
MedicationAdministrationSupported Profiles
  Medication Administration Profileversion: 0.2.0)		yyyy
FamilyHistorySupported Profiles
  Cancer Family Member Historyversion: 0.2.0)		yyyy
ListSupported Profiles
  Therapy Line Profileversion: 0.2.0)		y

Resource Conformance: supported Patient

Base System Profile
Cancer Patient Profileversion: 0.2.0)
Profile Conformance
SHALL
Reference Policy
literal

Interaction summary
  • Supports create, read, update, delete.

Resource Conformance: supported Condition

Core FHIR Resource
Condition
Reference Policy
literal
Interaction summary
  • Supports create, read, update, delete.

Supported Profiles

Primary Cancer Condition Profileversion: 0.2.0)
Secondary Cancer Condition Profileversion: 0.2.0)

Resource Conformance: supported Observation

Core FHIR Resource
Observation
Reference Policy
literal
Interaction summary
  • Supports create, read, update, delete.

Supported Profiles

Tumor Marker Profileversion: 0.2.0)
Cancer Risk Assessment Profileversion: 0.2.0)
Genomic Variant Profileversion: 0.2.0)
Tumor Mutational Burden Profileversion: 0.2.0)
Microsatellite Instability Profileversion: 0.2.0)
Loss of Heterozygosity Profileversion: 0.2.0)
Homologous Recombination Deficiency Profileversion: 0.2.0)
Tumor Neoantigen Burden Profileversion: 0.2.0)
Aneuploid Score Profileversion: 0.2.0)
Cancer Stageversion: 0.2.0)
TNM Stage Groupversion: 0.2.0)
Comorbidities Profileversion: 0.2.0)
Lifestyle Profileversion: 0.2.0)
Karnofsky Performance Status Profileversion: 0.2.0)
ECOG Performance Status Profileversion: 0.2.0)
Imaging Disease Status Profileversion: 0.2.0)
TNM Primary Tumor Categoryversion: 0.2.0)
TNM Distant Metastases Categoryversion: 0.2.0)
TNM Regional Nodes Categoryversion: 0.2.0)
TNM Lymphatic Invasion Categoryversion: 0.2.0)
TNM Perineural Invasion Categoryversion: 0.2.0)
TNM Residual Tumor Categoryversion: 0.2.0)
TNM Grade Categoryversion: 0.2.0)
Serum Tumor Marker Level Categoryversion: 0.2.0)
Venous Invasion Categoryversion: 0.2.0)
Observation Body Height Profileversion: 4.0.1)
Observation Body Weight Profileversion: 4.0.1)
Observation Body Temperature Profileversion: 4.0.1)
Observation Body Mass Index Profileversion: 4.0.1)
Observation Blood Pressure Profileversion: 4.0.1)

Resource Conformance: supported Procedure

Core FHIR Resource
Procedure
Reference Policy
literal
Interaction summary
  • Supports create, read, update, delete.

Supported Profiles

Surgical Procedure Profileversion: 0.2.0)
Radiotherapy Summary Profileversion: 0.2.0)
Tumor Board Reviewversion: 0.2.0)
Molecular Tumor Board Reviewversion: 0.2.0)

Resource Conformance: supported MedicationAdministration

Core FHIR Resource
MedicationAdministration
Reference Policy
literal
Interaction summary
  • Supports create, read, update, delete.

Supported Profiles

Medication Administration Profileversion: 0.2.0)

Resource Conformance: supported FamilyHistory

​Core FHIR Resource
FamilyHistory
Reference Policy
literal
Interaction summary
  • Supports create, read, update, delete.

Supported Profiles

Cancer Family Member Historyversion: 0.2.0)

Resource Conformance: supported List

Core FHIR Resource
List
Reference Policy
literal
Interaction summary
  • Supports read.

Supported Profiles

Therapy Line Profileversion: 0.2.0)