Onconova Implementation Guide
0.2.0 - ci-build

Onconova Implementation Guide - Local Development build (v0.2.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

Resource Profile: OnconovaMedicationAdministration - Detailed Descriptions

Active as of 2026-03-18

Definitions for the onconova-medication-administration resource profile.

Guidance on how to interpret the contents of this table can be foundhere

0. MedicationAdministration
Definition

Describes the event of a patient consuming or otherwise being administered a medication. This may be as simple as swallowing a tablet or it may be a long running infusion. Related resources tie this event to the authorizing prescription, and the specific encounter between patient and health care practitioner.

ShortAdministration of medication to a patient
Control0..*
Is Modifierfalse
Summaryfalse
Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
dom-6: A resource should have narrative for robust management (text.`div`.exists())
mcode-reason-required: One of reasonCode or reasonReference SHALL be present (reasonCode.exists() or reasonReference.exists())
termination-reason-code-invariant: When status is stopped, only certain statusReason values are allowed (status = 'stopped' and statusReason.exists() and statusReason.coding.exists() implies statusReason.coding.exists(system = 'http://snomed.info/sct' and (code = '182992009' or code = '266721009' or code = '407563006' or code = '160932005' or code = '105480006' or code = '184081006' or code = '309846006' or code = '399307001' or code = '419620001' or code = '7058009' or code = '443729008' or code = '77386006')))
termination-reason-invariant: Certain statusReason values are allowed only when status is stopped (statusReason.exists() and statusReason.coding.exists( system = 'http://snomed.info/sct' and (code = '182992009' or code = '266721009' or code = '407563006' or code = '160932005' or code = '105480006' or code = '184081006' or code = '309846006' or code = '399307001' or code = '419620001' or code = '7058009' or code = '443729008' or code = '77386006')) implies status = 'stopped')
o-med-req-1: The subject element is required and must be provided. (subject.exists())
o-med-req-2: The effectivePeriod element is required and must be provided. (effectivePeriod.exists())
o-med-req-3: The treatmentIntent extension is required and must be provided. (extension('http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-procedure-intent').exists())
o-med-req-4: The medicationCodeableConcept element is required and must be provided. (medicationCodeableConcept.exists() and medicationCodeableConcept.coding.exists())
2. MedicationAdministration.implicitRules
Definition

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

ShortA set of rules under which this content was created
Comments

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.

Control0..1
Typeuri
Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
4. MedicationAdministration.extension
Definition

An Extension


May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

ShortExtensionAdditional content defined by implementations
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control10..*
TypeExtension
Is Modifierfalse
Must Supporttrue
Summaryfalse
Alternate Namesextensions, user content
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
SlicingThis element introduces a set of slices on MedicationAdministration.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • value @ url
  • 6. MedicationAdministration.extension:treatmentIntent
    Slice NametreatmentIntent
    Definition

    The purpose of a treatment, medication, or procedure.

    ShortProcedure Intent Extension
    Control1..1
    This element is affected by the following invariants: ele-1
    TypeExtension(Procedure Intent Extension) (Extension Type: CodeableConcept)
    Is Modifierfalse
    Must Supporttrue
    Obligations
      ObligationsActor
      SHALL:populateCreator (Onconova)
      SHOULD:persistConsumer (Onconova)
      SHOULD:populate-if-knownCreator (Onconova)
      SHOULD:persistConsumer (Onconova)
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      8. MedicationAdministration.extension:treatmentIntent.extension
      Definition

      An Extension


      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

      ShortExtensionAdditional content defined by implementations
      Comments

      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

      Control0..0*
      TypeExtension
      Is Modifierfalse
      Summaryfalse
      Alternate Namesextensions, user content
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      SlicingThis element introduces a set of slices on MedicationAdministration.extension.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
      • value @ url
      • 10. MedicationAdministration.extension:treatmentIntent.url
        Definition

        Source of the definition for the extension code - a logical name or a URL.

        Shortidentifies the meaning of the extension
        Comments

        The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

        Control1..1
        Typeuri
        Is Modifierfalse
        XML FormatIn the XML format, this property is represented as an attribute.
        Summaryfalse
        Fixed Valuehttp://hl7.org/fhir/us/mcode/StructureDefinition/mcode-procedure-intent
        12. MedicationAdministration.extension:treatmentIntent.value[x]
        Definition

        Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).

        ShortValue of extension
        Control10..1
        BindingThe codes SHALL be taken from For codes, see Treatment Intents Value Set
        (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-treatment-intents)
        TypeCodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
        Is Modifierfalse
        Summaryfalse
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        14. MedicationAdministration.extension:normalizationBasis
        Slice NamenormalizationBasis
        Definition

        Not used in this profile

        ShortNot used in this profile
        Control0..1
        This element is affected by the following invariants: ele-1
        TypeExtension(Normalization Basis Extension) (Extension Type: CodeableConcept)
        Is Modifierfalse
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        16. MedicationAdministration.extension:combinedWith
        Slice NamecombinedWith
        Definition

        Indicates which medication administrations were given in combination with the current medication administration.

        ShortOther medication administered in combination
        Control0..*
        TypeExtension(Medication Administration Combined With) (Extension Type: Reference(Medication Administration Profile))
        Is Modifierfalse
        Must Supporttrue
        Obligations
          ObligationsActor
          SHALL:populate-if-knownCreator (Onconova)
          SHOULD:persistConsumer (Onconova)
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
          18. MedicationAdministration.extension:cycles
          Slice Namecycles
          Definition

          Indicates the total number of cycles for this medication administration.

          ShortTotal number of cycles for this medication
          Control0..1
          TypeExtension(Medication Administration Cycles) (Extension Type: integer)
          Is Modifierfalse
          Must Supporttrue
          Obligations
            ObligationsActor
            SHALL:populateCreator (Onconova)
            SHOULD:persistConsumer (Onconova)
            Summaryfalse
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            20. MedicationAdministration.extension:therapyLine
            Slice NametherapyLine
            Definition

            A reference to the therapy line associated with this treatment.

            ShortReference to the therapy line associated with this treatment
            Control0..1
            TypeExtension(Therapy Line Reference) (Extension Type: Reference(Therapy Line Profile))
            Is Modifierfalse
            Must Supporttrue
            Obligations
              ObligationsActor
              MAY:ignoreCreator (Onconova)
              MAY:persistConsumer (Onconova)
              Summaryfalse
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
              22. MedicationAdministration.extension:adjunctiveRole
              Slice NameadjunctiveRole
              Definition

              Indicates the role of this medication administration in the context of the overall treatment plan.

              ShortRole of this medication in the overall treatment plan
              Control0..1
              TypeExtension(Medication Administration Adjunctive Role) (Extension Type: CodeableConcept)
              Is Modifierfalse
              Must Supporttrue
              Obligations
                ObligationsActor
                SHALL:populate-if-knownCreator (Onconova)
                SHOULD:persistConsumer (Onconova)
                Summaryfalse
                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                24. MedicationAdministration.extension:isPrimaryTherapy
                Slice NameisPrimaryTherapy
                Definition

                Indicates whether this medication administration is the primary therapy within a therapy line.

                ShortIndicates if this medication is the primary therapy within a therapy line
                Control0..1
                TypeExtension(Medication Administration Is Primary Therapy) (Extension Type: boolean)
                Is Modifierfalse
                Must Supporttrue
                Obligations
                  ObligationsActor
                  MAY:ignoreCreator (Onconova)
                  MAY:persistConsumer (Onconova)
                  Summaryfalse
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                  26. MedicationAdministration.modifierExtension
                  Definition

                  May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                  ShortExtensions that cannot be ignored
                  Comments

                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                  Control0..*
                  TypeExtension
                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
                  Summaryfalse
                  Requirements

                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                  Alternate Namesextensions, user content
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                  28. MedicationAdministration.partOf
                  Definition

                  Not used in this profile


                  A larger event of which this particular event is a component or step.

                  ShortNot used in this profilePart of referenced event
                  Control0..*
                  TypeReference(MedicationAdministration, Procedure, MedicationAdministration, Procedure)
                  Is Modifierfalse
                  Summarytrue
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  30. MedicationAdministration.status
                  Definition

                  Not used in this profile


                  Will generally be set to show that the administration has been completed. For some long running administrations such as infusions, it is possible for an administration to be started but not completed or it may be paused while some other process is under way.

                  ShortNot used in this profilein-progress | not-done | on-hold | completed | entered-in-error | stopped | unknown
                  Comments

                  This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

                  Control1..1
                  BindingThe codes SHALL be taken from MedicationAdministration Status Codeshttp://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1
                  (required to http://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1)

                  A set of codes indicating the current status of a MedicationAdministration.

                  Typecode
                  Is Modifiertrue because This element is labelled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid
                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                  Must Supporttrue
                  Summarytrue
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  32. MedicationAdministration.statusReason
                  Definition

                  A code indicating why the administration was not performed.

                  ShortReason administration not performed
                  Control10..1*
                  BindingThe codes SHALL be taken from For example codes, see Treatment Termination Reasons Value Sethttp://hl7.org/fhir/ValueSet/reason-medication-not-given-codes|4.0.1
                  (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-treatment-termination-reasons)
                  TypeCodeableConcept
                  Is Modifierfalse
                  Must Supporttrue
                  Obligations
                    ObligationsActor
                    SHOULD:populate-if-knownCreator (Onconova)
                    SHOULD:persistConsumer (Onconova)
                    Summaryfalse
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    34. MedicationAdministration.medication[x]
                    Definition

                    Identifies the medication that was administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications.

                    ShortWhat was administered
                    Comments

                    If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource.

                    Control1..1
                    BindingThe codes SHALL be taken from For example codes, see Antineoplastic Agents Value Sethttp://hl7.org/fhir/ValueSet/medication-codes|4.0.1
                    (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-antineoplastic-agents)
                    TypeCodeableConcept, Reference(Medication)
                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                    Is Modifierfalse
                    Must Supporttrue
                    Obligations
                      ObligationsActor
                      SHALL:populateCreator (Onconova)
                      SHOULD:persistConsumer (Onconova)
                      Summarytrue
                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                      36. MedicationAdministration.subject
                      Definition

                      The patient receiving the medication.


                      The person or animal or group receiving the medication.

                      ShortWho received medication
                      Control1..1
                      TypeReference(Cancer Patient Profile, Patient, Group)
                      Is Modifierfalse
                      Must Supporttrue
                      Obligations
                        ObligationsActor
                        SHALL:populateCreator (Onconova)
                        SHOULD:persistConsumer (Onconova)
                        Summarytrue
                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                        38. MedicationAdministration.context
                        Definition

                        Not used in this profile


                        The visit, admission, or other contact between patient and health care provider during which the medication administration was performed.

                        ShortNot used in this profileEncounter or Episode of Care administered as part of
                        Control0..1
                        TypeReference(Encounter, EpisodeOfCare, Encounter, EpisodeOfCare)
                        Is Modifierfalse
                        Summaryfalse
                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                        40. MedicationAdministration.supportingInformation
                        Definition

                        Not used in this profile


                        Additional information (for example, patient height and weight) that supports the administration of the medication.

                        ShortNot used in this profileAdditional information to support administration
                        Control0..*
                        TypeReference(Resource, Resource)
                        Is Modifierfalse
                        Summaryfalse
                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                        42. MedicationAdministration.effective[x]
                        Definition

                        A specific date/time or interval of time during which the administration took place (or did not take place, when the 'notGiven' attribute is true). For many administrations, such as swallowing a tablet the use of dateTime is more appropriate.

                        ShortStart and end time of administration
                        Control1..1
                        TypePeriod, dateTime
                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                        Is Modifierfalse
                        Must Supporttrue
                        Obligations
                          ObligationsActor
                          SHALL:populateCreator (Onconova)
                          SHOULD:persistConsumer (Onconova)
                          Summarytrue
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          44. MedicationAdministration.performer
                          Definition

                          Not used in this profile


                          Indicates who or what performed the medication administration and how they were involved.

                          ShortNot used in this profileWho performed the medication administration and what they did
                          Control0..*
                          TypeBackboneElement
                          Is Modifierfalse
                          Summarytrue
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          46. MedicationAdministration.performer.modifierExtension
                          Definition

                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                          ShortExtensions that cannot be ignored even if unrecognized
                          Comments

                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                          Control0..*
                          TypeExtension
                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                          Summarytrue
                          Requirements

                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                          Alternate Namesextensions, user content, modifiers
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                          48. MedicationAdministration.performer.actor
                          Definition

                          Indicates who or what performed the medication administration.

                          ShortWho performed the medication administration
                          Control1..1
                          TypeReference(Practitioner, PractitionerRole, Patient, RelatedPerson, Device, Practitioner, PractitionerRole, Patient, RelatedPerson, Device)
                          Is Modifierfalse
                          Summarytrue
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          50. MedicationAdministration.reasonCode
                          Definition

                          Not used in this profile


                          A code indicating why the medication was given.

                          ShortNot used in this profileReason administration performed
                          Control0..*
                          BindingUnless not suitable, these codes SHALL be taken from For example codes, see Cancer Disorder Value Sethttp://hl7.org/fhir/ValueSet/reason-medication-given-codes|4.0.1
                          (extensible to http://hl7.org/fhir/us/mcode/ValueSet/mcode-cancer-disorder-vs)
                          TypeCodeableConcept
                          Is Modifierfalse
                          Must Supporttrue
                          Summaryfalse
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          52. MedicationAdministration.reasonReference
                          Definition

                          Condition or observation that supports why the medication was administered.

                          ShortThe condition(s) that motivated the medication administrationCondition or observation that supports why the medication was administered
                          Comments

                          This is a reference to a condition that is the reason for the medication request. If only a code exists, use reasonCode.

                          Control10..*
                          TypeReference(Primary Cancer Condition Profile, Secondary Cancer Condition Profile, Condition, Observation, DiagnosticReport)
                          Is Modifierfalse
                          Must Supporttrue
                          Must Support TypesNo must-support rules about the choice of types/profiles
                          Obligations
                            ObligationsActor
                            SHALL:populateCreator (Onconova)
                            SHOULD:persistConsumer (Onconova)
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            54. MedicationAdministration.request
                            Definition

                            Not used in this profile


                            The original request, instruction or authority to perform the administration.

                            ShortNot used in this profileRequest administration performed against
                            Comments

                            This is a reference to the MedicationRequest where the intent is either order or instance-order. It should not reference MedicationRequests where the intent is any other value.

                            Control0..1
                            TypeReference(MedicationRequest, MedicationRequest)
                            Is Modifierfalse
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            56. MedicationAdministration.dosage
                            Definition

                            Describes the medication dosage information details e.g. dose, rate, site, route, etc.

                            ShortDetails of how medication was taken
                            Control0..1
                            TypeBackboneElement
                            Is Modifierfalse
                            Must Supporttrue
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            mad-1: SHALL have at least one of dosage.dose or dosage.rate[x] (dose.exists() or rate.exists())
                            mad-1: SHALL have at least one of dosage.dose or dosage.rate[x] (dose.exists() or rate.exists())
                            58. MedicationAdministration.dosage.modifierExtension
                            Definition

                            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                            ShortExtensions that cannot be ignored even if unrecognized
                            Comments

                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                            Control0..*
                            TypeExtension
                            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                            Summarytrue
                            Requirements

                            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                            Alternate Namesextensions, user content, modifiers
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())

                            Guidance on how to interpret the contents of this table can be foundhere

                            0. MedicationAdministration
                            Invariantso-med-req-1: The subject element is required and must be provided. (subject.exists())
                            o-med-req-2: The effectivePeriod element is required and must be provided. (effectivePeriod.exists())
                            o-med-req-3: The treatmentIntent extension is required and must be provided. (extension('http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-procedure-intent').exists())
                            o-med-req-4: The medicationCodeableConcept element is required and must be provided. (medicationCodeableConcept.exists() and medicationCodeableConcept.coding.exists())
                            2. MedicationAdministration.extension
                            Control1..?
                            4. MedicationAdministration.extension:treatmentIntent
                            Slice NametreatmentIntent
                            Control1..?
                            Obligations
                              ObligationsActor
                              SHALL:populateCreator (Onconova)
                              SHOULD:persistConsumer (Onconova)
                              SHOULD:populate-if-knownCreator (Onconova)
                              SHOULD:persistConsumer (Onconova)
                              6. MedicationAdministration.extension:treatmentIntent.value[x]
                              BindingThe codes SHALL be taken from Treatment Intents Value Set
                              (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-treatment-intents)
                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                              8. MedicationAdministration.extension:normalizationBasis
                              Slice NamenormalizationBasis
                              Definition

                              Not used in this profile

                              ShortNot used in this profile
                              10. MedicationAdministration.extension:combinedWith
                              Slice NamecombinedWith
                              ShortOther medication administered in combination
                              Control0..*
                              TypeExtension(Medication Administration Combined With) (Extension Type: Reference(Medication Administration Profile))
                              Obligations
                                ObligationsActor
                                SHALL:populate-if-knownCreator (Onconova)
                                SHOULD:persistConsumer (Onconova)
                                12. MedicationAdministration.extension:cycles
                                Slice Namecycles
                                ShortTotal number of cycles for this medication
                                Control0..1
                                TypeExtension(Medication Administration Cycles) (Extension Type: integer)
                                Obligations
                                  ObligationsActor
                                  SHALL:populateCreator (Onconova)
                                  SHOULD:persistConsumer (Onconova)
                                  14. MedicationAdministration.extension:therapyLine
                                  Slice NametherapyLine
                                  ShortReference to the therapy line associated with this treatment
                                  Control0..1
                                  TypeExtension(Therapy Line Reference) (Extension Type: Reference(Therapy Line Profile))
                                  Obligations
                                    ObligationsActor
                                    MAY:ignoreCreator (Onconova)
                                    MAY:persistConsumer (Onconova)
                                    16. MedicationAdministration.extension:adjunctiveRole
                                    Slice NameadjunctiveRole
                                    ShortRole of this medication in the overall treatment plan
                                    Control0..1
                                    TypeExtension(Medication Administration Adjunctive Role) (Extension Type: CodeableConcept)
                                    Obligations
                                      ObligationsActor
                                      SHALL:populate-if-knownCreator (Onconova)
                                      SHOULD:persistConsumer (Onconova)
                                      18. MedicationAdministration.extension:isPrimaryTherapy
                                      Slice NameisPrimaryTherapy
                                      ShortIndicates if this medication is the primary therapy within a therapy line
                                      Control0..1
                                      TypeExtension(Medication Administration Is Primary Therapy) (Extension Type: boolean)
                                      Obligations
                                        ObligationsActor
                                        MAY:ignoreCreator (Onconova)
                                        MAY:persistConsumer (Onconova)
                                        20. MedicationAdministration.partOf
                                        Definition

                                        Not used in this profile

                                        ShortNot used in this profile
                                        22. MedicationAdministration.status
                                        Definition

                                        Not used in this profile

                                        ShortNot used in this profile
                                        24. MedicationAdministration.statusReason
                                        Control1..1
                                        BindingThe codes SHALL be taken from Treatment Termination Reasons Value Set
                                        (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-treatment-termination-reasons)
                                        Obligations
                                          ObligationsActor
                                          SHOULD:populate-if-knownCreator (Onconova)
                                          SHOULD:persistConsumer (Onconova)
                                          26. MedicationAdministration.medication[x]
                                          BindingThe codes SHALL be taken from Antineoplastic Agents Value Set
                                          (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-antineoplastic-agents)
                                          TypeCodeableConcept, Reference(Medication)
                                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                          Obligations
                                            ObligationsActor
                                            SHALL:populateCreator (Onconova)
                                            SHOULD:persistConsumer (Onconova)
                                            28. MedicationAdministration.subject
                                            TypeReference(Cancer Patient Profile)
                                            Obligations
                                              ObligationsActor
                                              SHALL:populateCreator (Onconova)
                                              SHOULD:persistConsumer (Onconova)
                                              30. MedicationAdministration.context
                                              Definition

                                              Not used in this profile

                                              ShortNot used in this profile
                                              32. MedicationAdministration.supportingInformation
                                              Definition

                                              Not used in this profile

                                              ShortNot used in this profile
                                              34. MedicationAdministration.effective[x]
                                              TypePeriod, dateTime
                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                              Obligations
                                                ObligationsActor
                                                SHALL:populateCreator (Onconova)
                                                SHOULD:persistConsumer (Onconova)
                                                36. MedicationAdministration.performer
                                                Definition

                                                Not used in this profile

                                                ShortNot used in this profile
                                                38. MedicationAdministration.reasonCode
                                                Definition

                                                Not used in this profile

                                                ShortNot used in this profile
                                                40. MedicationAdministration.reasonReference
                                                ShortThe condition(s) that motivated the medication administration
                                                Control1..?
                                                TypeReference(Primary Cancer Condition Profile, Secondary Cancer Condition Profile)
                                                Obligations
                                                  ObligationsActor
                                                  SHALL:populateCreator (Onconova)
                                                  SHOULD:persistConsumer (Onconova)
                                                  42. MedicationAdministration.request
                                                  Definition

                                                  Not used in this profile

                                                  ShortNot used in this profile
                                                  44. MedicationAdministration.dosage
                                                  Must Supporttrue

                                                  Guidance on how to interpret the contents of this table can be foundhere

                                                  0. MedicationAdministration
                                                  Definition

                                                  Describes the event of a patient consuming or otherwise being administered a medication. This may be as simple as swallowing a tablet or it may be a long running infusion. Related resources tie this event to the authorizing prescription, and the specific encounter between patient and health care practitioner.

                                                  ShortAdministration of medication to a patient
                                                  Control0..*
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
                                                  dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
                                                  dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
                                                  dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
                                                  dom-6: A resource should have narrative for robust management (text.`div`.exists())
                                                  mcode-reason-required: One of reasonCode or reasonReference SHALL be present (reasonCode.exists() or reasonReference.exists())
                                                  termination-reason-code-invariant: When status is stopped, only certain statusReason values are allowed (status = 'stopped' and statusReason.exists() and statusReason.coding.exists() implies statusReason.coding.exists(system = 'http://snomed.info/sct' and (code = '182992009' or code = '266721009' or code = '407563006' or code = '160932005' or code = '105480006' or code = '184081006' or code = '309846006' or code = '399307001' or code = '419620001' or code = '7058009' or code = '443729008' or code = '77386006')))
                                                  termination-reason-invariant: Certain statusReason values are allowed only when status is stopped (statusReason.exists() and statusReason.coding.exists( system = 'http://snomed.info/sct' and (code = '182992009' or code = '266721009' or code = '407563006' or code = '160932005' or code = '105480006' or code = '184081006' or code = '309846006' or code = '399307001' or code = '419620001' or code = '7058009' or code = '443729008' or code = '77386006')) implies status = 'stopped')
                                                  o-med-req-1: The subject element is required and must be provided. (subject.exists())
                                                  o-med-req-2: The effectivePeriod element is required and must be provided. (effectivePeriod.exists())
                                                  o-med-req-3: The treatmentIntent extension is required and must be provided. (extension('http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-procedure-intent').exists())
                                                  o-med-req-4: The medicationCodeableConcept element is required and must be provided. (medicationCodeableConcept.exists() and medicationCodeableConcept.coding.exists())
                                                  2. MedicationAdministration.id
                                                  Definition

                                                  The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

                                                  ShortLogical id of this artifact
                                                  Comments

                                                  The only time that a resource does not have an id is when it is being submitted to the server using a create operation.

                                                  Control0..1
                                                  Typeid
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  4. MedicationAdministration.meta
                                                  Definition

                                                  The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

                                                  ShortMetadata about the resource
                                                  Control0..1
                                                  TypeMeta
                                                  Is Modifierfalse
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  6. MedicationAdministration.implicitRules
                                                  Definition

                                                  A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

                                                  ShortA set of rules under which this content was created
                                                  Comments

                                                  Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.

                                                  Control0..1
                                                  Typeuri
                                                  Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation
                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                  Summarytrue
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  8. MedicationAdministration.language
                                                  Definition

                                                  The base language in which the resource is written.

                                                  ShortLanguage of the resource content
                                                  Comments

                                                  Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

                                                  Control0..1
                                                  BindingThe codes SHOULD be taken from CommonLanguages
                                                  (preferred to http://hl7.org/fhir/ValueSet/languages)

                                                  A human language.

                                                  Additional BindingsPurpose
                                                  AllLanguagesMax Binding
                                                  Typecode
                                                  Is Modifierfalse
                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  10. MedicationAdministration.text
                                                  Definition

                                                  A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

                                                  ShortText summary of the resource, for human interpretation
                                                  Comments

                                                  Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.

                                                  Control0..1
                                                  TypeNarrative
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Alternate Namesnarrative, html, xhtml, display
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  12. MedicationAdministration.contained
                                                  Definition

                                                  These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.

                                                  ShortContained, inline Resources
                                                  Comments

                                                  This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.

                                                  Control0..*
                                                  TypeResource
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Alternate Namesinline resources, anonymous resources, contained resources
                                                  14. MedicationAdministration.extension
                                                  Definition

                                                  An Extension

                                                  ShortExtension
                                                  Control1..*
                                                  TypeExtension
                                                  Is Modifierfalse
                                                  Must Supporttrue
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  SlicingThis element introduces a set of slices on MedicationAdministration.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                  • value @ url
                                                  • 16. MedicationAdministration.extension:treatmentIntent
                                                    Slice NametreatmentIntent
                                                    Definition

                                                    The purpose of a treatment, medication, or procedure.

                                                    ShortProcedure Intent Extension
                                                    Control1..1
                                                    This element is affected by the following invariants: ele-1
                                                    TypeExtension(Procedure Intent Extension) (Extension Type: CodeableConcept)
                                                    Is Modifierfalse
                                                    Must Supporttrue
                                                    Obligations
                                                      ObligationsActor
                                                      SHALL:populateCreator (Onconova)
                                                      SHOULD:persistConsumer (Onconova)
                                                      SHOULD:populate-if-knownCreator (Onconova)
                                                      SHOULD:persistConsumer (Onconova)
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      18. MedicationAdministration.extension:treatmentIntent.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      20. MedicationAdministration.extension:treatmentIntent.extension
                                                      Definition

                                                      An Extension

                                                      ShortExtension
                                                      Control0..0
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      SlicingThis element introduces a set of slices on MedicationAdministration.extension.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                      • value @ url
                                                      • 22. MedicationAdministration.extension:treatmentIntent.url
                                                        Definition

                                                        Source of the definition for the extension code - a logical name or a URL.

                                                        Shortidentifies the meaning of the extension
                                                        Comments

                                                        The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

                                                        Control1..1
                                                        Typeuri
                                                        Is Modifierfalse
                                                        XML FormatIn the XML format, this property is represented as an attribute.
                                                        Summaryfalse
                                                        Fixed Valuehttp://hl7.org/fhir/us/mcode/StructureDefinition/mcode-procedure-intent
                                                        24. MedicationAdministration.extension:treatmentIntent.value[x]
                                                        Definition

                                                        Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).

                                                        ShortValue of extension
                                                        Control1..1
                                                        BindingThe codes SHALL be taken from Treatment Intents Value Set
                                                        (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-treatment-intents)
                                                        TypeCodeableConcept
                                                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                        Is Modifierfalse
                                                        Summaryfalse
                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                        26. MedicationAdministration.extension:normalizationBasis
                                                        Slice NamenormalizationBasis
                                                        Definition

                                                        Not used in this profile

                                                        ShortNot used in this profile
                                                        Control0..1
                                                        This element is affected by the following invariants: ele-1
                                                        TypeExtension(Normalization Basis Extension) (Extension Type: CodeableConcept)
                                                        Is Modifierfalse
                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                        28. MedicationAdministration.extension:combinedWith
                                                        Slice NamecombinedWith
                                                        Definition

                                                        Indicates which medication administrations were given in combination with the current medication administration.

                                                        ShortOther medication administered in combination
                                                        Control0..*
                                                        TypeExtension(Medication Administration Combined With) (Extension Type: Reference(Medication Administration Profile))
                                                        Is Modifierfalse
                                                        Must Supporttrue
                                                        Obligations
                                                          ObligationsActor
                                                          SHALL:populate-if-knownCreator (Onconova)
                                                          SHOULD:persistConsumer (Onconova)
                                                          Summaryfalse
                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                          30. MedicationAdministration.extension:cycles
                                                          Slice Namecycles
                                                          Definition

                                                          Indicates the total number of cycles for this medication administration.

                                                          ShortTotal number of cycles for this medication
                                                          Control0..1
                                                          TypeExtension(Medication Administration Cycles) (Extension Type: integer)
                                                          Is Modifierfalse
                                                          Must Supporttrue
                                                          Obligations
                                                            ObligationsActor
                                                            SHALL:populateCreator (Onconova)
                                                            SHOULD:persistConsumer (Onconova)
                                                            Summaryfalse
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                            32. MedicationAdministration.extension:therapyLine
                                                            Slice NametherapyLine
                                                            Definition

                                                            A reference to the therapy line associated with this treatment.

                                                            ShortReference to the therapy line associated with this treatment
                                                            Control0..1
                                                            TypeExtension(Therapy Line Reference) (Extension Type: Reference(Therapy Line Profile))
                                                            Is Modifierfalse
                                                            Must Supporttrue
                                                            Obligations
                                                              ObligationsActor
                                                              MAY:ignoreCreator (Onconova)
                                                              MAY:persistConsumer (Onconova)
                                                              Summaryfalse
                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                              34. MedicationAdministration.extension:adjunctiveRole
                                                              Slice NameadjunctiveRole
                                                              Definition

                                                              Indicates the role of this medication administration in the context of the overall treatment plan.

                                                              ShortRole of this medication in the overall treatment plan
                                                              Control0..1
                                                              TypeExtension(Medication Administration Adjunctive Role) (Extension Type: CodeableConcept)
                                                              Is Modifierfalse
                                                              Must Supporttrue
                                                              Obligations
                                                                ObligationsActor
                                                                SHALL:populate-if-knownCreator (Onconova)
                                                                SHOULD:persistConsumer (Onconova)
                                                                Summaryfalse
                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                36. MedicationAdministration.extension:isPrimaryTherapy
                                                                Slice NameisPrimaryTherapy
                                                                Definition

                                                                Indicates whether this medication administration is the primary therapy within a therapy line.

                                                                ShortIndicates if this medication is the primary therapy within a therapy line
                                                                Control0..1
                                                                TypeExtension(Medication Administration Is Primary Therapy) (Extension Type: boolean)
                                                                Is Modifierfalse
                                                                Must Supporttrue
                                                                Obligations
                                                                  ObligationsActor
                                                                  MAY:ignoreCreator (Onconova)
                                                                  MAY:persistConsumer (Onconova)
                                                                  Summaryfalse
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                  38. MedicationAdministration.modifierExtension
                                                                  Definition

                                                                  May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                  ShortExtensions that cannot be ignored
                                                                  Comments

                                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                  Control0..*
                                                                  TypeExtension
                                                                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
                                                                  Summaryfalse
                                                                  Requirements

                                                                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                  Alternate Namesextensions, user content
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                  40. MedicationAdministration.identifier
                                                                  Definition

                                                                  Identifiers associated with this Medication Administration that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server.

                                                                  ShortExternal identifier
                                                                  Comments

                                                                  This is a business identifier, not a resource identifier.

                                                                  NoteThis is a business identifier, not a resource identifier (see discussion)
                                                                  Control0..*
                                                                  TypeIdentifier
                                                                  Is Modifierfalse
                                                                  Summaryfalse
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  42. MedicationAdministration.instantiates
                                                                  Definition

                                                                  A protocol, guideline, orderset, or other definition that was adhered to in whole or in part by this event.

                                                                  ShortInstantiates protocol or definition
                                                                  Control0..*
                                                                  Typeuri
                                                                  Is Modifierfalse
                                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                  Summarytrue
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  44. MedicationAdministration.partOf
                                                                  Definition

                                                                  Not used in this profile

                                                                  ShortNot used in this profile
                                                                  Control0..*
                                                                  TypeReference(MedicationAdministration, Procedure)
                                                                  Is Modifierfalse
                                                                  Summarytrue
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  46. MedicationAdministration.status
                                                                  Definition

                                                                  Not used in this profile

                                                                  ShortNot used in this profile
                                                                  Comments

                                                                  This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

                                                                  Control1..1
                                                                  BindingThe codes SHALL be taken from MedicationAdministration Status Codes
                                                                  (required to http://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1)

                                                                  A set of codes indicating the current status of a MedicationAdministration.

                                                                  Typecode
                                                                  Is Modifiertrue because This element is labelled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid
                                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                  Must Supporttrue
                                                                  Summarytrue
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  48. MedicationAdministration.statusReason
                                                                  Definition

                                                                  A code indicating why the administration was not performed.

                                                                  ShortReason administration not performed
                                                                  Control1..1
                                                                  BindingThe codes SHALL be taken from Treatment Termination Reasons Value Set
                                                                  (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-treatment-termination-reasons)
                                                                  TypeCodeableConcept
                                                                  Is Modifierfalse
                                                                  Must Supporttrue
                                                                  Obligations
                                                                    ObligationsActor
                                                                    SHOULD:populate-if-knownCreator (Onconova)
                                                                    SHOULD:persistConsumer (Onconova)
                                                                    Summaryfalse
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    50. MedicationAdministration.category
                                                                    Definition

                                                                    Indicates where the medication is expected to be consumed or administered.

                                                                    ShortType of medication usage
                                                                    Control0..1
                                                                    BindingThe codes SHOULD be taken from MedicationAdministration Category Codes
                                                                    (preferred to http://hl7.org/fhir/ValueSet/medication-admin-category)

                                                                    A coded concept describing where the medication administered is expected to occur.

                                                                    TypeCodeableConcept
                                                                    Is Modifierfalse
                                                                    Summaryfalse
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    52. MedicationAdministration.medication[x]
                                                                    Definition

                                                                    Identifies the medication that was administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications.

                                                                    ShortWhat was administered
                                                                    Comments

                                                                    If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource.

                                                                    Control1..1
                                                                    BindingThe codes SHALL be taken from Antineoplastic Agents Value Set
                                                                    (required to http://onconova.github.io/fhir/ValueSet/onconova-vs-antineoplastic-agents)
                                                                    TypeCodeableConcept
                                                                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                    Is Modifierfalse
                                                                    Must Supporttrue
                                                                    Obligations
                                                                      ObligationsActor
                                                                      SHALL:populateCreator (Onconova)
                                                                      SHOULD:persistConsumer (Onconova)
                                                                      Summarytrue
                                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                      54. MedicationAdministration.subject
                                                                      Definition

                                                                      The patient receiving the medication.

                                                                      ShortWho received medication
                                                                      Control1..1
                                                                      TypeReference(Cancer Patient Profile)
                                                                      Is Modifierfalse
                                                                      Must Supporttrue
                                                                      Obligations
                                                                        ObligationsActor
                                                                        SHALL:populateCreator (Onconova)
                                                                        SHOULD:persistConsumer (Onconova)
                                                                        Summarytrue
                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                        56. MedicationAdministration.context
                                                                        Definition

                                                                        Not used in this profile

                                                                        ShortNot used in this profile
                                                                        Control0..1
                                                                        TypeReference(Encounter, EpisodeOfCare)
                                                                        Is Modifierfalse
                                                                        Summaryfalse
                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                        58. MedicationAdministration.supportingInformation
                                                                        Definition

                                                                        Not used in this profile

                                                                        ShortNot used in this profile
                                                                        Control0..*
                                                                        TypeReference(Resource)
                                                                        Is Modifierfalse
                                                                        Summaryfalse
                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                        60. MedicationAdministration.effective[x]
                                                                        Definition

                                                                        A specific date/time or interval of time during which the administration took place (or did not take place, when the 'notGiven' attribute is true). For many administrations, such as swallowing a tablet the use of dateTime is more appropriate.

                                                                        ShortStart and end time of administration
                                                                        Control1..1
                                                                        TypePeriod
                                                                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                        Is Modifierfalse
                                                                        Must Supporttrue
                                                                        Obligations
                                                                          ObligationsActor
                                                                          SHALL:populateCreator (Onconova)
                                                                          SHOULD:persistConsumer (Onconova)
                                                                          Summarytrue
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          62. MedicationAdministration.performer
                                                                          Definition

                                                                          Not used in this profile

                                                                          ShortNot used in this profile
                                                                          Control0..*
                                                                          TypeBackboneElement
                                                                          Is Modifierfalse
                                                                          Summarytrue
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          64. MedicationAdministration.performer.id
                                                                          Definition

                                                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                          ShortUnique id for inter-element referencing
                                                                          Control0..1
                                                                          Typestring
                                                                          Is Modifierfalse
                                                                          XML FormatIn the XML format, this property is represented as an attribute.
                                                                          Summaryfalse
                                                                          66. MedicationAdministration.performer.extension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                          ShortAdditional content defined by implementations
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifierfalse
                                                                          Summaryfalse
                                                                          Alternate Namesextensions, user content
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          68. MedicationAdministration.performer.modifierExtension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                          ShortExtensions that cannot be ignored even if unrecognized
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                          Summarytrue
                                                                          Requirements

                                                                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                          Alternate Namesextensions, user content, modifiers
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          70. MedicationAdministration.performer.function
                                                                          Definition

                                                                          Distinguishes the type of involvement of the performer in the medication administration.

                                                                          ShortType of performance
                                                                          Control0..1
                                                                          BindingFor example codes, see MedicationAdministration Performer Function Codes
                                                                          (example to http://hl7.org/fhir/ValueSet/med-admin-perform-function)

                                                                          A code describing the role an individual played in administering the medication.

                                                                          TypeCodeableConcept
                                                                          Is Modifierfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          72. MedicationAdministration.performer.actor
                                                                          Definition

                                                                          Indicates who or what performed the medication administration.

                                                                          ShortWho performed the medication administration
                                                                          Control1..1
                                                                          TypeReference(Practitioner, PractitionerRole, Patient, RelatedPerson, Device)
                                                                          Is Modifierfalse
                                                                          Summarytrue
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          74. MedicationAdministration.reasonCode
                                                                          Definition

                                                                          Not used in this profile

                                                                          ShortNot used in this profile
                                                                          Control0..*
                                                                          BindingUnless not suitable, these codes SHALL be taken from Cancer Disorder Value Set
                                                                          (extensible to http://hl7.org/fhir/us/mcode/ValueSet/mcode-cancer-disorder-vs)
                                                                          TypeCodeableConcept
                                                                          Is Modifierfalse
                                                                          Must Supporttrue
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          76. MedicationAdministration.reasonReference
                                                                          Definition

                                                                          Condition or observation that supports why the medication was administered.

                                                                          ShortThe condition(s) that motivated the medication administration
                                                                          Comments

                                                                          This is a reference to a condition that is the reason for the medication request. If only a code exists, use reasonCode.

                                                                          Control1..*
                                                                          TypeReference(Primary Cancer Condition Profile, Secondary Cancer Condition Profile)
                                                                          Is Modifierfalse
                                                                          Must Supporttrue
                                                                          Must Support TypesNo must-support rules about the choice of types/profiles
                                                                          Obligations
                                                                            ObligationsActor
                                                                            SHALL:populateCreator (Onconova)
                                                                            SHOULD:persistConsumer (Onconova)
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            78. MedicationAdministration.request
                                                                            Definition

                                                                            Not used in this profile

                                                                            ShortNot used in this profile
                                                                            Comments

                                                                            This is a reference to the MedicationRequest where the intent is either order or instance-order. It should not reference MedicationRequests where the intent is any other value.

                                                                            Control0..1
                                                                            TypeReference(MedicationRequest)
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            80. MedicationAdministration.device
                                                                            Definition

                                                                            The device used in administering the medication to the patient. For example, a particular infusion pump.

                                                                            ShortDevice used to administer
                                                                            Control0..*
                                                                            TypeReference(Device)
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            82. MedicationAdministration.note
                                                                            Definition

                                                                            Extra information about the medication administration that is not conveyed by the other attributes.

                                                                            ShortInformation about the administration
                                                                            Control0..*
                                                                            TypeAnnotation
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            84. MedicationAdministration.dosage
                                                                            Definition

                                                                            Describes the medication dosage information details e.g. dose, rate, site, route, etc.

                                                                            ShortDetails of how medication was taken
                                                                            Control0..1
                                                                            TypeBackboneElement
                                                                            Is Modifierfalse
                                                                            Must Supporttrue
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            mad-1: SHALL have at least one of dosage.dose or dosage.rate[x] (dose.exists() or rate.exists())
                                                                            86. MedicationAdministration.dosage.id
                                                                            Definition

                                                                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                            ShortUnique id for inter-element referencing
                                                                            Control0..1
                                                                            Typestring
                                                                            Is Modifierfalse
                                                                            XML FormatIn the XML format, this property is represented as an attribute.
                                                                            Summaryfalse
                                                                            88. MedicationAdministration.dosage.extension
                                                                            Definition

                                                                            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                            ShortAdditional content defined by implementations
                                                                            Comments

                                                                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                            Control0..*
                                                                            TypeExtension
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Alternate Namesextensions, user content
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                            90. MedicationAdministration.dosage.modifierExtension
                                                                            Definition

                                                                            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                            ShortExtensions that cannot be ignored even if unrecognized
                                                                            Comments

                                                                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                            Control0..*
                                                                            TypeExtension
                                                                            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                            Summarytrue
                                                                            Requirements

                                                                            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                            Alternate Namesextensions, user content, modifiers
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                            92. MedicationAdministration.dosage.text
                                                                            Definition

                                                                            Free text dosage can be used for cases where the dosage administered is too complex to code. When coded dosage is present, the free text dosage may still be present for display to humans.

                                                                            The dosage instructions should reflect the dosage of the medication that was administered.

                                                                            ShortFree text dosage instructions e.g. SIG
                                                                            Control0..1
                                                                            Typestring
                                                                            Is Modifierfalse
                                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            94. MedicationAdministration.dosage.site
                                                                            Definition

                                                                            A coded specification of the anatomic site where the medication first entered the body. For example, "left arm".

                                                                            ShortBody site administered to
                                                                            Comments

                                                                            If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension bodySite. May be a summary code, or a reference to a very precise definition of the location, or both.

                                                                            Control0..1
                                                                            BindingFor example codes, see SNOMEDCTAnatomicalStructureForAdministrationSiteCodes
                                                                            (example to http://hl7.org/fhir/ValueSet/approach-site-codes)

                                                                            A coded concept describing the site location the medicine enters into or onto the body.

                                                                            TypeCodeableConcept
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            96. MedicationAdministration.dosage.route
                                                                            Definition

                                                                            A code specifying the route or physiological path of administration of a therapeutic agent into or onto the patient. For example, topical, intravenous, etc.

                                                                            ShortPath of substance into body
                                                                            Control0..1
                                                                            BindingFor example codes, see SNOMEDCTRouteCodes
                                                                            (example to http://hl7.org/fhir/ValueSet/route-codes)

                                                                            A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.

                                                                            TypeCodeableConcept
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            98. MedicationAdministration.dosage.method
                                                                            Definition

                                                                            A coded value indicating the method by which the medication is intended to be or was introduced into or on the body. This attribute will most often NOT be populated. It is most commonly used for injections. For example, Slow Push, Deep IV.

                                                                            ShortHow drug was administered
                                                                            Comments

                                                                            One of the reasons this attribute is not used often, is that the method is often pre-coordinated with the route and/or form of administration. This means the codes used in route or form may pre-coordinate the method in the route code or the form code. The implementation decision about what coding system to use for route or form code will determine how frequently the method code will be populated e.g. if route or form code pre-coordinate method code, then this attribute will not be populated often; if there is no pre-coordination then method code may be used frequently.

                                                                            Control0..1
                                                                            BindingFor example codes, see SNOMEDCTAdministrationMethodCodes
                                                                            (example to http://hl7.org/fhir/ValueSet/administration-method-codes)

                                                                            A coded concept describing the technique by which the medicine is administered.

                                                                            TypeCodeableConcept
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            100. MedicationAdministration.dosage.dose
                                                                            Definition

                                                                            The amount of the medication given at one administration event. Use this value when the administration is essentially an instantaneous event such as a swallowing a tablet or giving an injection.

                                                                            ShortAmount of medication per dose
                                                                            Comments

                                                                            If the administration is not instantaneous (rate is present), this can be specified to convey the total amount administered over period of time of a single administration.

                                                                            Control0..1
                                                                            TypeQuantity(SimpleQuantity)
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            102. MedicationAdministration.dosage.rate[x]
                                                                            Definition

                                                                            Identifies the speed with which the medication was or will be introduced into the patient. Typically, the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time, e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours.

                                                                            ShortDose quantity per unit of time
                                                                            Comments

                                                                            If the rate changes over time, and you want to capture this in MedicationAdministration, then each change should be captured as a distinct MedicationAdministration, with a specific MedicationAdministration.dosage.rate, and the date time when the rate change occurred. Typically, the MedicationAdministration.dosage.rate element is not used to convey an average rate.

                                                                            Control0..1
                                                                            TypeChoice of: Ratio, Quantity(SimpleQuantity)
                                                                            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                            104. MedicationAdministration.eventHistory
                                                                            Definition

                                                                            A summary of the events of interest that have occurred, such as when the administration was verified.

                                                                            ShortA list of events of interest in the lifecycle
                                                                            Comments

                                                                            This might not include provenances for all versions of the request – only those deemed “relevant” or important. This SHALL NOT include the Provenance associated with this current version of the resource. (If that provenance is deemed to be a “relevant” change, it will need to be added as part of a later update. Until then, it can be queried directly as the Provenance that points to this version using _revinclude All Provenances should have some historical version of this Request as their subject.

                                                                            Control0..*
                                                                            TypeReference(Provenance)
                                                                            Is Modifierfalse
                                                                            Summaryfalse
                                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))