Onconova Implementation Guide
0.2.0 - ci-build

Onconova Implementation Guide - Local Development build (v0.2.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

ValueSet: Tumor Marker Tests

Official URL: http://onconova.github.io/fhir/ValueSet/onconova-vs-tumor-marker-tests Version: 0.2.0
Active as of 2026-03-18 Computable Name: TumorMarkerTests

ValueSet containing LOINC and NCI Thesaurus codes for tumor marker laboratory tests and measurements

References

Logical Definition (CLD)

This value set includes codes based on the following rules:

  • Include these codes as defined in http://loinc.org version Not Stated (use latest from terminology server)
    CodeDisplay
    2039-6Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
    19166-8Carcinoembryonic Ag [Units/volume] in Serum or Plasma
    19167-6Carcinoembryonic Ag [Moles/volume] in Serum or Plasma
    40618-1Cancer Ag 125 [Units/volume] in Serum or Plasma
    10334-1Cancer Ag 15-3 [Units/volume] in Serum or Plasma
    24108-3Cancer Ag 19-9 [Units/volume] in Serum or Plasma
    2011-5Cancer Ag 242 [Presence] in Serum or Plasma
    17842-6Cancer Ag 27-29 [Units/volume] in Serum or Plasma
    34256-8Cancer Ag 50 [Units/volume] in Serum or Plasma
    19189-0Cancer Ag 549 [Units/volume] in Serum or Plasma
    17843-4Cancer Ag 72-4 [Units/volume] in Serum or Plasma
    13127-6Cancer Ag DM/70K [Units/volume] in Serum or Plasma
    24474-9Cancer associated serum Ag [Units/volume] in Serum
    98117-5Fibroblast growth factor 2 [Mass/volume] in Serum or Plasma
    87832-2Fibroblast growth factor 21.intact [Mass/volume] in Serum or Plasma
    46699-5Fibroblast growth factor 23 [Units/volume] in Plasma
    54390-0Fibroblast growth factor 23.intact [Mass/volume] in Serum or Plasma
    104259-7Fibroblast growth factor 23 [Presence] in Tissue by FISH
    96461-9Gastrin releasing polypeptide prohormone [Mass/volume] in Serum or Plasma by Immunoassay
    54165-6Tumor necrosis factor binding protein [Units/volume] in Serum
    48663-9YKL-40 [Mass/volume] in Serum
    15060-7Enolase.neuron specific [Mass/volume] in Serum or Plasma
    19193-2Enolase.neuron specific [Units/volume] in Serum or Plasma
    2532-0Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
    9811-1Chromogranin A [Mass/volume] in Serum or Plasma
    25587-7Chromogranin A [Moles/volume] in Serum or Plasma
    47275-3S100 calcium binding protein B [Mass/volume] in Serum
    19195-7Prostate specific Ag [Units/volume] in Serum or Plasma
    2857-1Prostate specific Ag [Mass/volume] in Serum or Plasma
    19197-3Prostate specific Ag [Moles/volume] in Serum or Plasma
    1834-1Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
    19176-7Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
    19177-5Alpha-1-Fetoprotein [Moles/volume] in Serum or Plasma
    55869-2Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma
    21198-7Choriogonadotropin.beta subunit [Units/volume] in Serum or Plasma
    2111-3Choriogonadotropin.beta subunit [Moles/volume] in Serum or Plasma
    55868-4Choriogonadotropin.beta subunit [Multiple of the median] in Serum or Plasma
    25390-6Cytokeratin 19 [Mass/volume] in Serum or Plasma
    19182-5Cytokeratin 19 [Units/volume] in Serum or Plasma
    96044-3Human epididymis protein 4 [Mass/volume] in Serum or Plasma
    55180-4Human epididymis protein 4 [Moles/volume] in Serum or Plasma
    17248-6Melanin [Units/volume] in Serum or Plasma
    2607-0Melanin [Mass/volume] in Urine
    13238-1Epstein Barr virus Ab [Units/volume] in Serum
    49178-7Epstein Barr virus Ab [Presence] in Serum
    72383-3HER2 [Presence] in Tissue by Immunoassay
    14228-1Cells.estrogen receptor/cells in Tissue by Immune stain
    14230-7Cells.progesterone receptor/cells in Tissue by Immune stain
    29593-1Cells.Ki-67 nuclear Ag/cells in Tissue by Immune stain
    96272-0DNA mismatch repair protein Mlh3 [Presence] in Cancer specimen by Immune stain
    81691-8DNA mismatch repair protein Mlh1 [Presence] in Cancer specimen by Immune stain
    81692-6DNA mismatch repair protein Msh2 [Presence] in Cancer specimen by Immune stain
    81693-4DNA mismatch repair protein Msh6 [Presence] in Cancer specimen by Immune stain
    81694-2Mismatch repair endonuclease PMS2 [Presence] in Cancer specimen by Immune stain
    21614-3CDKN2A gene deletion [Presence] in Blood or Tissue by Molecular genetics method
    105077-2Human papilloma virus DNA [Presence] in Specimen
    5003-9Epstein Barr virus DNA [Presence] in Tissue by Probe
    108217-1Epstein Barr virus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection
  • Include these codes as defined in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl version Not Stated (use latest from terminology server)
    CodeDisplay
    C96593 Circulating Tumor Cell Count
    C199175 PD-L1 Immune Cell Score
    C184941 PD-L1 Tumor Proportion Score
    C176582 PD-L1 Combined Positive Score
    C185751 HER2/Neu Status by Immunohistochemistry
    C157165 AR Status by Immunohistochemistry
    C165984 Somatostatin Receptor Type 2 Measurement

 

Expansion

Expansion based on code system fragment http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl NCI Thesaurus version null

Expansion from tx.fhir.org based on Loinc v2.81

This value set contains at least 58 concepts

SystemCodeDisplay (en)InactivestatusJSONXML
http://loinc.org  2039-6Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
http://loinc.org  19166-8Carcinoembryonic Ag [Units/volume] in Serum or Plasma
http://loinc.org  19167-6Carcinoembryonic Ag [Moles/volume] in Serum or Plasma
http://loinc.org  40618-1Cancer Ag 125 [Units/volume] in Peritoneal fluid
http://loinc.org  10334-1Cancer Ag 125 [Units/volume] in Serum or Plasma
http://loinc.org  24108-3Cancer Ag 19-9 [Units/volume] in Serum or Plasma
http://loinc.org  2011-5Cancer Ag 242 [Presence] in Serum or Plasma
http://loinc.org  17842-6Cancer Ag 27-29 [Units/volume] in Serum or Plasma
http://loinc.org  34256-8Cancer Ag 50 [Units/volume] in Serum or Plasma
http://loinc.org  19189-0Cancer Ag 549 [Units/volume] in Serum or Plasma
http://loinc.org  17843-4Cancer Ag 72-4 [Units/volume] in Serum or Plasma
http://loinc.org  13127-6Cancer Ag DM/70K [Units/volume] in Serum or Plasma
http://loinc.org  24474-9Cancer associated serum Ag [Units/volume] in Serum
http://loinc.org  98117-5Fibroblast growth factor 2 [Mass/volume] in Serum or Plasma
http://loinc.org  87832-2Fibroblast growth factor 21.intact [Mass/volume] in Serum or Plasma
http://loinc.org  46699-5Fibroblast growth factor 23 [Units/volume] in Plasma
http://loinc.org  54390-0Fibroblast growth factor 23.intact [Mass/volume] in Serum or Plasma
http://loinc.org  104259-7Fibroblast growth factor 23 [Presence] in Tissue by FISH
http://loinc.org  96461-9Gastrin releasing polypeptide prohormone [Mass/volume] in Serum or Plasma by Immunoassay
http://loinc.org  54165-6Tumor necrosis factor binding protein [Units/volume] in SeruminactiveDISCOURAGED
http://loinc.org  48663-9YKL-40 [Mass/volume] in Serum
http://loinc.org  15060-7Enolase.neuron specific [Mass/volume] in Serum or Plasma
http://loinc.org  19193-2Enolase.neuron specific [Units/volume] in Serum or Plasma
http://loinc.org  2532-0Lactate dehydrogenase [Enzymatic activity/volume] in Serum or PlasmainactiveDISCOURAGED
http://loinc.org  9811-1Chromogranin A [Mass/volume] in Serum or Plasma
http://loinc.org  25587-7Chromogranin A [Moles/volume] in Serum or Plasma
http://loinc.org  47275-3S100 calcium binding protein B [Mass/volume] in Serum
http://loinc.org  19195-7Prostate specific Ag [Units/volume] in Serum or Plasma
http://loinc.org  2857-1Prostate specific Ag [Mass/volume] in Serum or Plasma
http://loinc.org  19197-3Prostate specific Ag [Moles/volume] in Serum or Plasma
http://loinc.org  1834-1Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
http://loinc.org  19176-7Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
http://loinc.org  19177-5Alpha-1-Fetoprotein [Moles/volume] in Serum or Plasma
http://loinc.org  55869-2Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma
http://loinc.org  21198-7Choriogonadotropin.beta subunit [Units/volume] in Serum or Plasma
http://loinc.org  2111-3Choriogonadotropin.beta subunit [Moles/volume] in Serum or Plasma
http://loinc.org  55868-4Choriogonadotropin.beta subunit [Multiple of the median] in Serum or Plasma
http://loinc.org  25390-6Cytokeratin 19 [Mass/volume] in Serum or Plasma
http://loinc.org  19182-5Cytokeratin 19 [Units/volume] in Serum or Plasma
http://loinc.org  96044-3Human epididymis protein 4 [Mass/volume] in Serum or Plasma
http://loinc.org  55180-4Human epididymis protein 4 [Moles/volume] in Serum or Plasma
http://loinc.org  17248-6Melanin [Units/volume] in Serum or PlasmainactiveDISCOURAGED
http://loinc.org  2607-0Melanin [Mass/volume] in Urine
http://loinc.org  13238-1Epstein Barr virus Ab [Units/volume] in Serum
http://loinc.org  49178-7Epstein Barr virus Ab [Presence] in Serum
http://loinc.org  72383-3HER2 [Presence] in Tissue by Immunoassay
http://loinc.org  14228-1Cells.estrogen receptor/cells in Tissue by Immune stain
http://loinc.org  14230-7Cells.progesterone receptor/cells in Tissue by Immune stain
http://loinc.org  29593-1Cells.Ki-67 nuclear Ag/cells in Tissue by Immune stain
http://loinc.org  96272-0DNA mismatch repair protein Mlh3 [Presence] in Cancer specimen by Immune stain
http://loinc.org  81691-8DNA mismatch repair protein Mlh1 [Presence] in Cancer specimen by Immune stain
http://loinc.org  81692-6DNA mismatch repair protein Msh2 [Presence] in Cancer specimen by Immune stain
http://loinc.org  81693-4DNA mismatch repair protein Msh6 [Presence] in Cancer specimen by Immune stain
http://loinc.org  81694-2Mismatch repair endonuclease PMS2 [Presence] in Cancer specimen by Immune stain
http://loinc.org  21614-3CDKN2A gene deletion [Presence] in Blood or Tissue by Molecular genetics method
http://loinc.org  105077-2Human papilloma virus DNA [Presence] in Specimen
http://loinc.org  5003-9Epstein Barr virus DNA [Presence] in Tissue by Probe
http://loinc.org  108217-1Epstein Barr virus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection

Explanation of the columns that may appear on this page:

Level A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code The code (used as the code in the resource instance)
Display The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition An explanation of the meaning of the concept
Comments Additional notes about how to use the code